BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction. - Test2 - elhamkhani - TriplyDB

BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

http://www.wikidata.org/entity/Q33936571

about

Epigenetic Regulation of Bone Remodeling and Its Impacts in Osteoporosis Functions of BET proteins in erythroid gene expression BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer.Chemical probes targeting epigenetic proteins: Applications beyond oncology.BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle.Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity Macrophage functions in lean and obese adipose tissue.Role of Regulators of G Protein Signaling Proteins in Bone Physiology and Pathophysiology.N,N Dimethylacetamide a drug excipient that acts as bromodomain ligand for osteoporosis treatment.Epigenetics and its role in periodontal diseases: a state-of-the-art review.The role of Toll-like receptors in periodontitis.Epigenetics and Periodontitis: A Contemporary Review.Epigenetic drug discovery: breaking through the immune barrier.Immune disease-associated variants in gene enhancers point to BET epigenetic mechanisms for therapeutic intervention.A Novel Epi-drug Therapy Based on the Suppression of BET Family Epigenetic Readers.Genetic Susceptibility Contributing to Periodontal and Cardiovascular Disease.Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential.Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay.Epigenetic regulation in bacterial infections: targeting histone deacetylases.Histone Adduction and Its Functional Impact on Epigenetics The BET/BRD inhibitor JQ1 improves brain plasticity in WT and APP mice.Current Concepts of Epigenetics and Its Role in Periodontitis.In silico design and bioevaluation of selective benzotriazepine BRD4 inhibitors with potent antiosteoclastogenic activity.Influence of N-methyl pyrrolidone on the activity of the pulp-dentine complex and bone integrity during osteoporosis.The BET Bromodomain Inhibitor JQ1 Suppresses Chondrosarcoma Cell Growth via Regulation of YAP/p21/c-Myc Signaling.Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation.BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment.Letter to the Editor, "BET inhibitor JQ1 blocks inflammation and bone destruction".N-methyl pyrrolidone (NMP) inhibits lipopolysaccharide-induced inflammation by suppressing NF-κB signaling.Epigenetic control of macrophage polarization: implications for targeting tumor-associated macrophages.JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

http://www.wikidata.org/entity/Q33936571

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2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.

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Journal of Dental Research

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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction

@en

P2093

D Murray

http://www.w3.org/2001/XMLSchema#string

J Chen

http://www.w3.org/2001/XMLSchema#string

J Cheng

http://www.w3.org/2001/XMLSchema#string

L Yu

http://www.w3.org/2001/XMLSchema#string

L Zhang

http://www.w3.org/2001/XMLSchema#string

L Zheng

http://www.w3.org/2001/XMLSchema#string

Q Tu

http://www.w3.org/2001/XMLSchema#string

S Meng

http://www.w3.org/2001/XMLSchema#string

X Zhou

http://www.w3.org/2001/XMLSchema#string

Y Tang

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition

Small-molecule inhibition of BRDT for male contraception.

Suppression of inflammation by a synthetic histone mimic

Control of inflammation and periodontitis

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

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