Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.

Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.

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http://www.wikidata.org/entity/Q33974599

Q33974599

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Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer The Ubiquitination of NF-κB Subunits in the Control of Transcription The Regulation of NF-κB Subunits by Phosphorylation NF-κB, the first quarter-century: remarkable progress and outstanding questions The role of aberrant proteolysis in lymphomagenesis NFKB2 mutation in common variable immunodeficiency and isolated adrenocorticotropic hormone deficiency: A case report and review of literature NF-kappaB: a multifaceted transcription factor regulated at several levels Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis Ubiquitin signalling in the NF-kappaB pathway Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation.The noncanonical NF-κB pathway.The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.Immunoglobulin light chains activate nuclear factor-κB in renal epithelial cells through a Src-dependent mechanism.Regulated protein turnover: snapshots of the proteasome in action.NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma.Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology DEPTOR ubiquitination and destruction by SCF(β-TrCP).Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling.TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway.Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin.Specification of DNA binding activity of NF-kappaB proteins Antiviral activity of innate immune protein ISG15.The NF-kappaB family of transcription factors and its regulation.Non-canonical NF-κB signaling pathway.Regulation of NF-κB by TNF family cytokines.Non-conventional functions for NF-κB members: the dark side of NF-κB.Role of the ubiquitin proteasome system in hematologic malignancies.Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes Cell fate decisions regulated by K63 ubiquitination of tumor necrosis factor receptor 1.Mitogen-Activated Protein Kinase 14 Promotes AKI.Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation.Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells.Role for protein kinase Ctheta (PKCtheta) in TCR/CD28-mediated signaling through the canonical but not the non-canonical pathway for NF-kappaB activation.Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1.MLN4924 sensitizes monocytes and maturing dendritic cells for TNF-dependent and -independent necroptosis.The origins and evolution of ubiquitination sites.

P2860

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P2860

Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.

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http://www.wikidata.org/entity/Q33974599

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2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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