Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
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Cullin-RING ubiquitin ligases: global regulation and activation cyclesAssociation of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosomeCullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cellsDifferential regulation of sentrinized proteins by a novel sentrin-specific proteaseThe amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neuronsIdentification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteinsConservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimerCalcium-dependent regulation of tumour necrosis factor-alpha receptor signalling by copineThe ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptorsSelective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.E2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationAn intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaThe Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathwaysPlaying Tag with HIF: The VHL StoryThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairCullin family proteins and tumorigenesis: genetic association and molecular mechanismsInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyStructural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYMEStructure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester TransferA Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function ScreenE2-binding surface on Uba3 β-grasp domain undergoes a conformational transitionExpression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1)Ubiquitylation, neddylation and the DNA damage responseA dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivoTargeting of NEDD8 and its conjugates for proteasomal degradation by NUB1The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1Substrate-mediated regulation of cullin neddylationTbata modulates thymic stromal cell proliferation and thymus functionDegradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complexOvercoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cellsIdentification of a multifunctional binding site on Ubc9p required for Smt3p conjugation.Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells.Regulation of the G1 to S transition by the ubiquitin pathway.HyperISGylation of Old World monkey ISG15 in human cells.
P2860
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P2860
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@ast
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en-gb
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@nl
type
label
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@ast
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en-gb
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@nl
prefLabel
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@ast
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en-gb
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@nl
P2860
P921
P356
P1476
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
@en
P2860
P304
P356
10.1074/JBC.274.17.12036
P407
P577
1999-04-23T00:00:00Z