The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34
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The novel human DNA helicase hFBH1 is an F-box proteinPriming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrateSelective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationCUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.Proximity-induced activation of human Cdc34 through heterologous dimerization.Solution structure and backbone dynamics of an N-terminal ubiquitin-like domain in the GLUT4-regulating protein, TUGThe Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimerAllosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp7860th residues of ubiquitin and Nedd8 are located out of E2-binding surfaces, but are important for K48 ubiquitin-linkageA new crystal form of Lys48-linked diubiquitinSelective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin LigaseIdentification and characterization of DEN1, a deneddylase of the ULP familyDEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1Substrate-mediated regulation of cullin neddylationRegulation of the NEDD8 conjugation system by a splicing variant, NUB1L.The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination.The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe.Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.Nedd8 on cullin: building an expressway to protein destruction.Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligaseSCFhFBH1 can act as helicase and E3 ubiquitin ligaseUbiquitin-conjugating enzyme Cdc34 and ubiquitin ligase Skp1-cullin-F-box ligase (SCF) interact through multiple conformations.The RUB/Nedd8 conjugation pathway is required for early development in ArabidopsisMono-ubiquitination drives nuclear export of the human DCN1-like protein hDCNL1Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activityThe ubiquitin-proteasome pathway and plant development.Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosisThe ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei.Signaling, polyubiquitination, trafficking, and inclusions: sequestosome 1/p62's role in neurodegenerative disease.Suramin inhibits cullin-RING E3 ubiquitin ligases.Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation.Multimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tailsThe acidic tail of the Cdc34 ubiquitin-conjugating enzyme functions in both binding to and catalysis with ubiquitin ligase SCFCdc4.A snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination.The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation.Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains.The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105.SCCRO (DCUN1D1) promotes nuclear translocation and assembly of the neddylation E3 complex.
P2860
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P2860
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@ast
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@en
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@nl
type
label
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@ast
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@en
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@nl
prefLabel
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@ast
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@en
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@nl
P2093
P2860
P356
P1476
The Nedd8-conjugated ROC1-CUL1 ...... in assembly catalyzed by Cdc34
@en
P2093
Angus Chen
Kenneth Wu
Peilin Tan
Zhen-Qiang Pan
P2860
P304
P356
10.1074/JBC.M108008200
P407
P577
2002-01-04T00:00:00Z