Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell line
about
Telomere dysfunction and chromosome instabilityEfficient repair of DNA double-strand breaks in malignant cells with structural instability.Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line.Telomere Biology-Insights into an Intriguing Phenomenon.Telomere loss as a mechanism for chromosome instability in human cancerCanonical histone H2Ba and H2A.X dimerize in an opposite genomic localization to H2A.Z/H2B.Z dimers in Toxoplasma gondii.The role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line.Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair.PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells.Mechanisms of telomere loss and their consequences for chromosome instability.Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation.DNA double-strand breaks in human induced pluripotent stem cell reprogramming and long-term in vitro culturingLow-grade chromosomal mosaicism in human somatic and embryonic stem cell populations.Inter-telomeric recombination is present in telomerase-positive human cells.Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements.Differences in the recruitment of DNA repair proteins at subtelomeric and interstitial I-SceI endonuclease-induced DNA double-strand breaks.
P2860
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P2860
Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell line
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2009 nî lūn-bûn
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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2009 թվականի հունիսին հրատարակված գիտական հոդված
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
Increased sensitivity of subte ...... ks in a human cancer cell line
@ast
Increased sensitivity of subte ...... ks in a human cancer cell line
@en
type
label
Increased sensitivity of subte ...... ks in a human cancer cell line
@ast
Increased sensitivity of subte ...... ks in a human cancer cell line
@en
prefLabel
Increased sensitivity of subte ...... ks in a human cancer cell line
@ast
Increased sensitivity of subte ...... ks in a human cancer cell line
@en
P2093
P2860
P1433
P1476
Increased sensitivity of subte ...... ks in a human cancer cell line
@en
P2093
Avanti Kulkarni
Douglas Miller
Gloria E Reynolds
Géraldine Pottier
John P Murnane
Laure Sabatier
Marine Granger-Locatelli
Oliver Zschenker
P2860
P304
P356
10.1016/J.DNAREP.2009.05.004
P577
2009-06-18T00:00:00Z