Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
about
Promiscuous DNA synthesis by human DNA polymerase θDNA Damage and Pulmonary HypertensionDNA polymerase θ (POLQ), double-strand break repair, and cancerMammalian polymerase θ promotes alternative NHEJ and suppresses recombinationDrosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repairAnalysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.Error-Prone Repair of DNA Double-Strand Breaks.POLQ in breast cancer.Human DNA polymerase θ grasps the primer terminus to mediate DNA repairHaving a direct look: analysis of DNA damage and repair mechanisms by next generation sequencing.Recent progress in targeting cancer.Single-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites.Impact of the DNA polymerase Theta on the DNA replication program.A role for human homologous recombination factors in suppressing microhomology-mediated end joiningEstrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.DNA polymerase POLQ and cellular defense against DNA damage.Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joiningDNA polymerases and cancer.The DNA resection protein CtIP promotes mammary tumorigenesis.DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotidesStop pulling my strings - what telomeres taught us about the DNA damage response.Base excision repair targets for cancer therapyBiological and therapeutic relevance of nonreplicative DNA polymerases to cancer.Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.A role for DNA polymerase θ in the timing of DNA replication.Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells.Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.Dual loss of human POLQ and LIG4 abolishes random integration.Gene expression-based risk score in diffuse large B-cell lymphoma.Identification of upregulated genes in oral squamous cell carcinomas.A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions.Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.
P2860
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P2860
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@ast
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@en
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@nl
type
label
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@ast
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@en
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@nl
prefLabel
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@ast
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@en
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@nl
P2093
P2860
P356
P1433
P1476
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
@en
P2093
Francesca M Buffa
Geoff S Higgins
Remko Prevo
W Gillies McKenna
P2860
P304
P356
10.18632/ONCOTARGET.124
P407
P577
2010-07-01T00:00:00Z