High-efficiency bypass of DNA damage by human DNA polymerase Q - Test2 - elhamkhani - TriplyDB

High-efficiency bypass of DNA damage by human DNA polymerase Q

High-efficiency bypass of DNA damage by human DNA polymerase Q

http://www.wikidata.org/entity/Q24561381

about

Promiscuous DNA synthesis by human DNA polymerase θ Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair A unique error signature for human DNA polymerase nu Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation Archaeal Hel308 helicase targets replication forks in vivo and in vitro and unwinds lagging strands Pathways for repairing and tolerating the spectrum of oxidative DNA lesions Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm Replication through an abasic DNA lesion: structural basis for adenine selectivity Learning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity Amino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA Polymerase DNA polymerase θ (POLQ), double-strand break repair, and cancer DNA Polymerase θ: A Unique Multifunctional End-Joining Machine A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability A transposon-derived DNA polymerase from Entamoeba histolytica displays intrinsic strand displacement, processivity and lesion bypass DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.Mechanism of suppression of chromosomal instability by DNA polymerase POLQ How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis Mitochondrial DNA replication: a PrimPol perspective.Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.A role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells.DNA polymerases in the mitochondria: A critical review of the evidence.Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer.Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity Overexpression of POLQ confers a poor prognosis in early breast cancer patients.DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability Mus308 processes oxygen and nitrogen ethylation DNA damage in germ cells of Drosophila.Endogenous DNA damage clusters in human skin, 3-D model, and cultured skin cells.DNA polymerases and somatic hypermutation of immunoglobulin genes Translesion synthesis across abasic lesions by human B-family and Y-family DNA polymerases α, δ, η, ι, κ, and REV1 Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study.Human DNA polymerase θ grasps the primer terminus to mediate DNA repair Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage.Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis A role for human homologous recombination factors in suppressing microhomology-mediated end joining Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

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High-efficiency bypass of DNA damage by human DNA polymerase Q

http://www.wikidata.org/entity/Q24561381

description

2004 nî lūn-bûn

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2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

High-efficiency bypass of DNA damage by human DNA polymerase Q

@ast

High-efficiency bypass of DNA damage by human DNA polymerase Q

@en

High-efficiency bypass of DNA damage by human DNA polymerase Q

@nl

type

label

High-efficiency bypass of DNA damage by human DNA polymerase Q

@ast

High-efficiency bypass of DNA damage by human DNA polymerase Q

@en

High-efficiency bypass of DNA damage by human DNA polymerase Q

@nl

prefLabel

High-efficiency bypass of DNA damage by human DNA polymerase Q

@ast

High-efficiency bypass of DNA damage by human DNA polymerase Q

@en

High-efficiency bypass of DNA damage by human DNA polymerase Q

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SJ.EMBOJ.7600424

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The EMBO Journal

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High-efficiency bypass of DNA damage by human DNA polymerase Q

@en

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Anthony Schuffert

http://www.w3.org/2001/XMLSchema#string

Chikahide Masutani

http://www.w3.org/2001/XMLSchema#string

Lee Wei Yang

http://www.w3.org/2001/XMLSchema#string

Mineaki Seki

http://www.w3.org/2001/XMLSchema#string

Shigenori Iwai

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase

Eukaryotic DNA Polymerases

Instability and decay of the primary structure of DNA

POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells

POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308

Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I

Mechanisms of accurate translesion synthesis by human DNA polymerase eta

Crystal structure of Thermus aquaticus DNA polymerase

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scholarly article

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685293

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10.1038/SJ.EMBOJ.7600424

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22

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23

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Richard Dean Wood

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2004-11-10T00:00:00Z

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8220059

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15496986

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526458

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