RGS4 and RGS5 are in vivo substrates of the N-end rule pathway - Test2 - elhamkhani - TriplyDB

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

http://www.wikidata.org/entity/Q34085136

about

The N-end rule pathway Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription Discovery of cellular regulation by protein degradation Galphao/i-stimulated proteosomal degradation of RGS20: a mechanism for temporal integration of Gs and Gi pathways Diversity of degradation signals in the ubiquitin-proteasome system Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway N-Terminal Acetylation-Targeted N-End Rule Proteolytic System: The Ac/N-End Rule Pathway Perspectives and Insights into the Competition for Aminoacyl-tRNAs between the Translational Machinery and for tRNA Dependent Non-Ribosomal Peptide Bond Formation Waterproofing crops: effective flooding survival strategies Arginylation-dependent neural crest cell migration is essential for mouse development Regulators of G-protein signaling in the heart and their potential as therapeutic targets.Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter.Global analysis of posttranslational protein arginylation.The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex.Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets.Generation of Artificial N-end Rule Substrate Proteins In Vivo and In Vitro.An improved workflow for quantitative N-terminal charge-based fractional diagonal chromatography (ChaFRADIC) to study proteolytic events in Arabidopsis thaliana.The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.Arginylation regulates intracellular actin polymer level by modulating actin properties and binding of capping and severing proteins.The substrate recognition domains of the N-end rule pathway.Arginyltransferase regulates alpha cardiac actin function, myofibril formation and contractility during heart development.Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis Rab family proteins regulate the endosomal trafficking and function of RGS4.Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations.The anti-apoptotic form of tyrosine kinase Lyn that is generated by proteolysis is degraded by the N-end rule pathway.Upregulation of RGS4 and downregulation of CPI-17 mediate inhibition of colonic muscle contraction by interleukin-1beta.Variations in Gnai2 and Rgs1 expression affect chemokine receptor signaling and the organization of secondary lymphoid organs.Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome Protein arginylation, a global biological regulator that targets actin cytoskeleton and the muscle A neurostimulant para-chloroamphetamine inhibits the arginylation branch of the N-end rule pathway.The N-end rule pathway and regulation by proteolysis MEKK1-MKK4-JNK-AP1 pathway negatively regulates Rgs4 expression in colonic smooth muscle cells UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells.Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.DHHC protein-dependent palmitoylation protects regulator of G-protein signaling 4 from proteasome degradation.Hemin binds to human cytoplasmic arginyl-tRNA synthetase and inhibits its catalytic activity

P2860

Q24598290-6B8BDFF4-9422-4649-9608-77F83F83B7BE Q24603948-C52861E1-46A6-48BD-9979-62A47CEC2695 Q24607508-A3E21BC8-51FB-4103-B470-4FFCEFAD21B0 Q24626665-148D3C91-9FB6-4A57-B25F-B0088C4DA7B5 Q24642979-069347E6-203A-4D7E-8838-AB4C2B2A179C Q24657529-B21A94AA-1778-4A07-B02D-9805E3401F73 Q26765414-7C379CEB-297B-4788-88C6-0B6B8938D315 Q26771234-FBCAD6D9-E2BC-438B-A903-CA9E283D43E4 Q27015952-488E655E-427D-4B42-8B1C-F2DA2D4281DE Q27348001-1AFDD699-8093-4B41-8E9A-91B6DCAE88EB Q27686777-E7F90B72-089C-43CC-878B-B6E1B0474AB1 Q27938697-5B297516-2D5F-48C0-ADF0-49558F783F27 Q28469307-792C9CBB-FB3C-48A5-84D6-C112BB5FD9BF Q28476173-37F1ADF8-162F-4878-B3F1-BEEB3060C422 Q28510458-4997B819-CDB4-41C3-9340-824687C6719F Q28594626-62185624-6194-4DB5-84FB-E09ECC7A27F2 Q28594993-F4531F7C-883C-4C9B-A3F4-F865B31EEF1F Q30176404-67F959B2-E0C2-43FD-BC49-5A6F524D7C17 Q30313311-34EA4EC1-4636-4534-B6D6-ABA0D2A2EE03 Q30314019-3D10C21D-C558-4653-BF01-7ED7C6A8F9B8 Q30316527-BF29AFE7-4DEF-4728-BBAE-137E6E44AE2D Q30397640-3F8831CD-A3B8-4EF7-9934-5D75B09722EB Q30435749-7F28FFC6-5E22-4758-9C6C-91E5469C709A Q30437353-CEAA7652-CD17-4004-BEB2-15F3382E91EE Q30484509-7350B59C-137C-4DDE-8757-13E0A1C17089 Q30505748-A83B018A-1DCC-4F55-BC85-996D13CCE57F Q30541823-01783EC7-1D86-4345-9F20-E87E45A92D88 Q30886015-F67157A6-9419-4E04-A196-F85D19C66319 Q33757090-0558DD57-3889-4E5B-A5BE-DEBD36A0044E Q34008216-4E2D656E-46A2-4248-A18B-B1AA991F7783 Q34012376-1C8DD34C-E02C-4FBB-B4B2-72F34E7CED83 Q34024105-3484D708-5C50-4587-9B9C-F90E8FE0C17F Q34055687-DCCB128A-53F4-4FC2-AED9-D6D6E154A9B9 Q34169532-EBC21D52-8C7E-43E6-84CD-2436AB325CF4 Q34189152-04F958FB-0B14-46E8-B871-D1C935B44522 Q34251193-4850E294-8B32-4D95-8B9B-A9BFAA3FFB2F Q34278026-5F1726DC-99BB-45A4-BD95-3764825D04A9 Q34310119-A62D77DE-2A3F-4B2B-BE07-8A867844561A Q34371923-FF91A944-6B65-4289-85EC-AD4B14B823DE Q34385919-31B71345-520F-4F25-8C7D-E6A35656C59A

P2860

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

http://www.wikidata.org/entity/Q34085136

description

2005 nî lūn-bûn

@nan

2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@ast

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@en

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@nl

type

label

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@ast

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@en

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@nl

prefLabel

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@ast

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@en

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@nl

P1433

Q34085136-97DDBFBA-53EC-4DBC-B7BD-92B572CE7895

P1476

Q34085136-205CF4F6-66A6-4D50-BBED-8C06C67738A5

P2093

Q34085136-0D1CA15E-A8DE-42DE-9713-29595EBBFFB4

Q34085136-1D678F67-6AD5-4251-8917-7FCAC2D9BFD5

Q34085136-3E8BF85B-0183-4DE5-9604-7F02B1BE2057

Q34085136-879D9599-79CA-43EE-84F3-691DC763AF43

Q34085136-AF0EDDDB-1A3A-4A32-BEFB-8F1111A6696E

Q34085136-B3078B73-F7F3-4E48-8F41-55A26A3B7E48

P2860

Q34085136-25CA3487-9F87-4524-B280-05AC944BE1AF

Q34085136-27A878C2-4105-48A0-A84F-80CA7A833036

Q34085136-2DE2EE11-42D8-458A-8DC6-7C495BB4DB1F

Q34085136-377E3478-51F9-449D-A9CE-258522E806CF

Q34085136-3FE88F26-5A61-4AC5-8F0E-7E4498DBE62A

Q34085136-41A053E3-FCEB-4ECB-ABA1-36C044EF323D

Q34085136-4730885B-4ECE-4E3B-84FD-44A9ED723916

Q34085136-5822C0FB-C66F-402B-8FC4-889327263B93

Q34085136-698F13BB-DD6D-4C45-8F3D-813B9CC3D4ED

Q34085136-86C6B5BF-2321-431A-9CC6-714841101FF5

P304

Q34085136-39AF6C84-1AC9-4ABD-A367-AA1705FD2F9D

P31

Q34085136-5FCE500B-D6F8-45E1-B0A9-889860D8DEAB

P356

Q34085136-8D73C1A7-2278-4232-8B33-53304A7CB736

P407

Q34085136-C759B4F2-A873-4CF9-AAAB-3CE7B20E3DB0

P433

Q34085136-006A2D2D-C0E5-4F99-8548-2DE68B180CB8

P478

Q34085136-49BDD3ED-2BA2-429A-93C9-C5F098C36082

P50

Q34085136-FA8C7FC2-03C4-4668-BB13-A1E3D31C200B

P577

Q34085136-265D3149-306E-452C-81B1-64A15294B0C1

P5875

Q34085136-3CB517E5-FF6F-4AD7-85D7-050A40E1A17A

P698

Q34085136-B93086BF-7B46-477D-A506-8760F1D46F39

P932

Q34085136-FBDF1F3D-3628-4AAC-83AD-E37C9A524A50

P356

PNAS.0507533102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

@en

P2093

Ilia V Davydov

http://www.w3.org/2001/XMLSchema#string

Jee Young An

http://www.w3.org/2001/XMLSchema#string

Kayoko Moroi

http://www.w3.org/2001/XMLSchema#string

Min Jae Lee

http://www.w3.org/2001/XMLSchema#string

Takafumi Tasaki

http://www.w3.org/2001/XMLSchema#string

Yong Tae Kwon

http://www.w3.org/2001/XMLSchema#string

P2860

Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.

The N-end rule: functions, mysteries, uses

Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

G protein pathways.

Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling

Characterization of RGS5 in regulation of G protein-coupled receptor signaling

P304

15030-15035

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0507533102

http://www.w3.org/2001/XMLSchema#string

P407

P433

42

http://www.w3.org/2001/XMLSchema#string

P478

102

http://www.w3.org/2001/XMLSchema#string

P50

P577

2005-10-10T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7549091

http://www.w3.org/2001/XMLSchema#string

P698

16217033

http://www.w3.org/2001/XMLSchema#string

P932

1257735

http://www.w3.org/2001/XMLSchema#string