Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells.
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Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1The balance of powers: Redox regulation of fibrogenic pathways in kidney injurySestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose TissuePast strategies and future directions for identifying AMP-activated protein kinase (AMPK) modulatorsJanus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domainsSestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injuryThe inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injurySestrins orchestrate cellular metabolism to attenuate aging.Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart.Regulatory effects of sestrin 3 (SESN3) in BCR-ABL expressing cellsInsulin Increases Sestrin 2 Content by Reducing Its Degradation through the PI 3 K/mTOR Signaling Pathway.Identification of an AMPK phosphorylation site in Drosophila TSC2 (gigas) that regulate cell growthAn ShRNA Based Genetic Screen Identified Sesn2 as a Potential Tumor Suppressor in Lung Cancer via Suppression of Akt-mTOR-p70S6K SignalingThe Expression of the Endogenous mTORC1 Inhibitor Sestrin 2 Is Induced by UVB and Balanced with the Expression Level of Sestrin 1.Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal InjuryTumor suppressive role of sestrin2 during colitis and colon carcinogenesis.Sestrin2 expression is a favorable prognostic factor in patients with non-small cell lung cancer.Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK.Sestrin regulation of TORC1: Is Sestrin a leucine sensor?Autophagy: regulation and role in developmentSestrin 2 and AMPK connect hyperglycemia to Nox4-dependent endothelial nitric oxide synthase uncoupling and matrix protein expression.SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophagesmir-101-3p is a key regulator of tumor metabolism in triple negative breast cancer targeting AMPK.SESN2 correlates with advantageous prognosis in hepatocellular carcinoma.Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer.Molecular pathways: reactive oxygen species homeostasis in cancer cells and implications for cancer therapy.AMP-activated protein kinase (AMPK) beyond metabolism: a novel genomic stress sensor participating in the DNA damage response pathway.Trichosanthes kirilowii fruits inhibit non-small cell lung cancer cell growth through mitotic cell-cycle arrest.Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner.Biochemical Basis of Sestrin Physiological Activities.Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation.A Metabolic Inhibitory Cocktail for Grave Cancers: Metformin, Pioglitazone and Lithium Combination in Treatment of Pancreatic Cancer and Glioblastoma Multiforme.Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis.Sestrin2 prevents age-related intolerance to ischemia and reperfusion injury by modulating substrate metabolism.Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation.Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials.Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines.Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.Quercetin Regulates Sestrin 2-AMPK-mTOR Signaling Pathway and Induces Apoptosis via Increased Intracellular ROS in HCT116 Colon Cancer Cells
P2860
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P2860
Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@ast
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@en
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@nl
type
label
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@ast
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@en
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@nl
prefLabel
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@ast
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@en
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@nl
P2093
P2860
P1433
P1476
Sestrin2 modulates AMPK subuni ...... iation in breast cancer cells.
@en
P2093
Gurmit Singh
Katja Linher-Melville
Theodoros Tsakiridis
Toran Sanli
P2860
P304
P356
10.1371/JOURNAL.PONE.0032035
P407
P577
2012-02-20T00:00:00Z