SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress
about
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway.Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA.Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage.Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.Targeting nuclear thymidylate biosynthesis.
P2860
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P2860
SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@ast
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@en
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@nl
type
label
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@ast
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@en
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@nl
prefLabel
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@ast
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@en
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@nl
P2093
P2860
P1433
P1476
SMUG1 but not UNG DNA glycosyl ...... cil induced replication stress
@en
P2093
Ashley R Brown
David Svilar
Michael D Wyatt
Pratik Nagaria
Robert W Sobol
Xiao-hong Wang
P2860
P356
10.1016/J.MRFMMM.2012.12.001
P407
P478
P577
2012-12-17T00:00:00Z