The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice - Test2 - elhamkhani - TriplyDB

The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice

The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice

http://www.wikidata.org/entity/Q21195685

about

Potential therapeutic effects of neurotrophins for acute and chronic neurological diseases The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin.A novel Alzheimer's disease drug candidate targeting inflammation and fatty acid metabolism.Back to the future with phenotypic screening J-147 a Novel Hydrazide Lead Compound to Treat Neurodegeneration: CeeTox(™) Safety and Genotoxicity Analysis.Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.A comprehensive multiomics approach toward understanding the relationship between aging and dementia.Progress in Alzheimer's disease research circa 2013: Is the glass half empty or half full?Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery.Neurotrophin strategies for neuroprotection: are they sufficient?Dicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of β-amyloid peptides and protects neuronal cells from β-amyloid-induced cytotoxicity.SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation.Neuroprotective effect of ipriflavone against scopolamine-induced memory impairment in rats.Fisetin Reduces the Impact of Aging on Behavior and Physiology in the Rapidly Aging SAMP8 Mouse.The mitochondrial ATP synthase is a shared drug target for aging and dementia.A novel curcumin derivative for the treatment of diabetic neuropathy.Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer's disease.A Potent Multi-functional Neuroprotective Derivative of Tetramethylpyrazine.

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The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice

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Alzheimers Research & Therapy

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The neurotrophic compound J147 ...... aged Alzheimer's disease mice

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Chandramouli Chiruta

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David Schubert

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Jennifer L Ehren

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Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

The Homer family proteins

Recent developments in Alzheimer's disease therapeutics

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

Purification and cloning of amyloid precursor protein beta-secretase from human brain

Neurotrophic factors in Alzheimer’s disease: role of axonal transport

New insights into brain BDNF function in normal aging and Alzheimer disease

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

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10.1186/ALZRT179

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Alzheimer's disease

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