Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.
about
Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugsKey Targets for Multi-Target Ligands Designed to Combat Neurodegeneration3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2Filling the void: a role for exercise induced BDNF and brain amyloid precursor protein processing.RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains.Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.Modulation of AβPP and GSK3β by Endoplasmic Reticulum Stress and Involvement in Alzheimer's Disease.BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus.Multi-Target Screening and Experimental Validation of Natural Products from Selaginella Plants against Alzheimer's Disease.Role of BACE1 in Alzheimer's synaptic function.Population density analysis for determining the protonation state of the catalytic dyad in BACE1-tertiary carbinamine-based inhibitor complex.Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer's Disease.Natural antisense transcripts in diseases: From modes of action to targeted therapies.Use of Peptides for the Management of Alzheimer's Disease: Diagnosis and Inhibition.BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions.Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer's DiseaseThe BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease
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P2860
Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.
@en
type
label
Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.
@en
prefLabel
Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.
@en
P2093
P2860
P1476
Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.
@en
P2093
Qingyuan Fan
Riqiang Yan
Robert Vassar
P2860
P304
P356
10.1016/J.NEUBIOREV.2016.03.025
P577
2016-04-01T00:00:00Z