Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
about
BRCA1 is an essential regulator of heart function and survival following myocardial infarctionATM activation by ionizing radiation requires BRCA1-associated BAAT1BRCA1 participates in DNA decatenationRoles of BRCA1 in centrosome duplicationA novel role for BRCA1 in regulating breast cancer cell spreading and motilityA requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpointBreastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriersBASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structuresZeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modificationCBP/p300 interact with and function as transcriptional coactivators of BRCA1Prospective identification of tumorigenic breast cancer cellsOvarian surface epithelium: family history and early events in ovarian cancerThe role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancerRegulation of BRCA1 expression and its relationship to sporadic breast cancerMouse models for breast cancerModeling Mammary Cancer in Mice Conference, Jackson Laboratory, Bar Harbor, Maine, 5-8 October, 1999Do we now have a relevant animal model for breast cancer?Role of BRCA gene dysfunction in breast and ovarian cancer predisposition.BRCA1 function in T lymphocytes: a cellular specificity of a different kind.Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer?Models of breast cancer: quo vadis, animal modeling?Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interferenceBRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolutionEvolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1 gene with missense sequence changes and in-frame deletions, but not polymorphismsConnecting the Dots: From DNA Damage and Repair to AgingInterplay between Fanconi anemia and homologous recombination pathways in genome integrityBRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?Modeling the study of DNA damage responses in miceIn vitro and in vivo approaches to study osteocyte biologyOver-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancerThe construction of transgenic and gene knockout/knockin mouse models of human diseaseBRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transitionLactation defect in a widely used MMTV-Cre transgenic line of miceGenetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closurePrepubertal physical activity up-regulates estrogen receptor beta, BRCA1 and p53 mRNA expression in the rat mammary glandOvca1 regulates cell proliferation, embryonic development, and tumorigenesisPalb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancerInactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
P2860
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P2860
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@ast
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@en
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@nl
type
label
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@ast
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@en
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@nl
prefLabel
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@ast
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@en
Conditional mutation of Brca1 ...... ogenesis and tumour formation.
@nl
P2093
P356
P1433
P1476
Conditional mutation of Brca1 ...... hogenesis and tumour formation
@en
P2093
Wynshaw-Boris A
P2888
P356
10.1038/8743
P407
P577
1999-05-01T00:00:00Z