Perforin: structure, function, and role in human immunopathology. - Test2 - elhamkhani - TriplyDB

Perforin: structure, function, and role in human immunopathology.

Perforin: structure, function, and role in human immunopathology.

http://www.wikidata.org/entity/Q34620426

about

Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression Human perforin mutations and susceptibility to multiple primary cancers The role of natural killer cells in pathogenesis of autoimmune diseases Mechanisms of Control of Mycobacterium tuberculosis by NK Cells: Role of Glutathione In vivo assessment of natural killer cell responses during chronic feline immunodeficiency virus infection Ancient Venom Systems: A Review on Cnidaria Toxins Imaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion.Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection.Decreased function of Fas and variations of the perforin gene in adult patients with primary immune thrombocytopenia.Effects of Treg cells and IDO on human epithelial ovarian cancer cells under hypoxic conditions Variations of the UNC13D gene in patients with autoimmune lymphoproliferative syndrome.Dynamics of the major histocompatibility complex class I processing and presentation pathway in the course of malaria parasite development in human hepatocytes: implications for vaccine development.The In Vivo Granulopoietic Response to Dexamethasone Injection Is Abolished in Perforin-Deficient Mutant Mice and Corrected by Lymphocyte Transfer from Nonsensitized Wild-Type Donors.Perforin: an important player in immune response.Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation Levetiracetam Prevents Perforin Mediated Neuronal Injury Induced by Acute Cerebral Ischemia Reperfusion.Cord blood PRF1 methylation patterns and risk of lower respiratory tract infections in infants: findings from the Ulm Birth Cohort Human NK cell lytic granules and regulation of their exocytosis Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors.The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures.Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption.STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.Perforinopathy: a spectrum of human immune disease caused by defective perforin delivery or function.Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity.Phenotype of NK Cells Determined on the Basis of Selected Immunological Parameters in Children Treated due to Acute Lymphoblastic Leukemia.Dendritic cells, macrophages, NK and CD8+ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B.The structure and function of mammalian membrane-attack complex/perforin-like proteins.Views of immunology: effector T cells.Insights into NK cell biology from human genetics and disease associations.Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier.Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking.Granzyme M: behind enemy lines.Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.Modularly Constructed Synthetic Granzyme B Molecule Enables Interrogation of Intracellular Proteases for Targeted Cytotoxicity.Benzenesulphonamide inhibitors of the cytolytic protein perforin.Necrosome core machinery: MLKL.Modern strategies and capabilities for activation of the immune response against tumor cells.

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Perforin: structure, function, and role in human immunopathology.

http://www.wikidata.org/entity/Q34620426

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年论文

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Perforin: structure, function, and role in human immunopathology.

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J.0105-2896.2010.00896.X

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Immunological Reviews

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Perforin: structure, function, and role in human immunopathology.

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Ilia Voskoboinik

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Katherine Baran

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Michelle A Dunstone

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P2860

Aids-related malignancies

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11

Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis

The global distribution of clinical episodes of Plasmodium falciparum malaria

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

Six novel mutations in the PRF1 gene in children with haemophagocytic lymphohistiocytosis

The major human and mouse granzymes are structurally and functionally divergent

Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients

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10.1111/J.0105-2896.2010.00896.X

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1

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235

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James C. Whisstock

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