Protein degradation pathways in Parkinson's disease: curse or blessing
about
Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoLinking F-box protein 7 and parkin to neuronal degeneration in Parkinson's disease (PD)Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's DiseasesWhat is the Clinical Significance of Cerebrospinal Fluid Biomarkers in Parkinson's disease? Is the Significance Diagnostic or Prognostic?Proteotoxicity: an underappreciated pathology in cardiac diseaseAmbroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cellsInteractions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseNigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synucleinMolecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathiesAntihypertensive agents and risk of Parkinson's disease: a nationwide cohort studyIntegrated molecular landscape of Parkinson's diseaseIncreased LINGO1 in the cerebellum of essential tremor patients.Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease.Alpha-synuclein levels in blood plasma decline with healthy aging.Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective AutophagyA Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevityThe activation sequence of cellular protein handling systems after proteasomal inhibition in dopaminergic cells.Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-diethylthiocarbamate (MeDETC) in Caenorhabditis elegans.DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease.Mitophagy and neurodegeneration: the zebrafish model system.Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases.Immunotherapy targeting α-synuclein, with relevance for future treatment of Parkinson's disease and other Lewy body disorders.Protective and toxic roles of dopamine in Parkinson's disease.Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.Sirtuins and proteolytic systems: implications for pathogenesis of synucleinopathies.Proteasome properties of hemocytes differ between the whiteleg shrimp Penaeus vannamei and the brown shrimp Crangon crangon (Crustacea, Decapoda).Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors.Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism.Clathrin-Dependent Uptake of Paraquat into SH-SY5Y Cells and Its Internalization into Different Subcellular Compartments.Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies.Of Pesticides and Men: a California Story of Genes and Environment in Parkinson's Disease.Impact of Plant-Derived Flavonoids on Neurodegenerative Diseases.Therapeutic potential of autophagy-enhancing agents in Parkinson's disease.Investigational α-synuclein aggregation inhibitors: hope for Parkinson's disease.Epigenetic regulation in Parkinson's disease.
P2860
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P2860
Protein degradation pathways in Parkinson's disease: curse or blessing
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Protein degradation pathways in Parkinson's disease: curse or blessing
@ast
Protein degradation pathways in Parkinson's disease: curse or blessing
@en
Protein degradation pathways in Parkinson's disease: curse or blessing
@nl
type
label
Protein degradation pathways in Parkinson's disease: curse or blessing
@ast
Protein degradation pathways in Parkinson's disease: curse or blessing
@en
Protein degradation pathways in Parkinson's disease: curse or blessing
@nl
prefLabel
Protein degradation pathways in Parkinson's disease: curse or blessing
@ast
Protein degradation pathways in Parkinson's disease: curse or blessing
@en
Protein degradation pathways in Parkinson's disease: curse or blessing
@nl
P2860
P3181
P1476
Protein degradation pathways in Parkinson's disease: curse or blessing
@en
P2093
Pamela J. McLean
P2860
P2888
P304
P3181
P356
10.1007/S00401-012-1004-6
P407
P577
2012-08-01T00:00:00Z
P5875
P6179
1023082322