DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.
about
Telomere dysfunction and chromosome instabilityComing of Age in the Life ofTelomere shortening in Barrett's mucosa and esophageal adenocarcinoma and its association with loss of heterozygosity.Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae.Meiotic aberrations during 2n pollen formation in Begonia.Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast.Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line.A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications.Reduced hTERT protein levels are associated with DNA aneuploidy in the colonic mucosa of patients suffering from longstanding ulcerative colitis.Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype.Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell lineThe FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.Telomere loss as a mechanism for chromosome instability in human cancerChromothripsis: breakage-fusion-bridge over and over again.Telomeres, chromosome instability and cancerThe role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line.SMAD5 gene expression, rearrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinomaLead Exposure Induces Telomere Instability in Human CellsSubtelomeric regions in mammalian cells are deficient in DNA double-strand break repair.Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramaticallyDe novo 7p partial trisomy characterized by subtelomeric FISH and whole-genome array in a girl with mental retardation.PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.Assessment of palindromes as platforms for DNA amplification in breast cancerMechanisms of telomere loss and their consequences for chromosome instability.Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cellsChromosomes and cancer cells.Chromosome 9 arm-specific telomere length and breast cancer riskGenomic instability demonstrates similarity between DCIS and invasive carcinomas.Telomere and telomerase as targets for cancer therapy.Implications of genomic instability in the diagnosis and treatment of breast cancer.Can cytogenetics explain the possible association between exposure to extreme low-frequency magnetic fields and Alzheimer's disease?The role of dicentric chromosome formation and secondary centromere deletion in the evolution of myeloid malignancy.Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes.Telomeres in cancer: tumour suppression and genome instability.Duplicated chromosomal fragments stabilize shortened telomeres in normal human IMR-90 cells before transition to senescence.Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements.Estimation of rearrangement phylogeny for cancer genomes.Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification.Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements.
P2860
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P2860
DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
DNA amplification by breakage/ ...... s in a human cancer cell line.
@ast
DNA amplification by breakage/ ...... s in a human cancer cell line.
@en
DNA amplification by breakage/ ...... s in a human cancer cell line.
@nl
type
label
DNA amplification by breakage/ ...... s in a human cancer cell line.
@ast
DNA amplification by breakage/ ...... s in a human cancer cell line.
@en
DNA amplification by breakage/ ...... s in a human cancer cell line.
@nl
prefLabel
DNA amplification by breakage/ ...... s in a human cancer cell line.
@ast
DNA amplification by breakage/ ...... s in a human cancer cell line.
@en
DNA amplification by breakage/ ...... s in a human cancer cell line.
@nl
P2093
P2860
P356
P1433
P1476
DNA amplification by breakage/ ...... ss in a human cancer cell line
@en
P2093
Bijan Fouladi
Géraldine Pottier
John P Murnane
Michelle Ricoul
P2860
P304
P356
10.1038/SJ.NEO.7900267
P577
2002-11-01T00:00:00Z