The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics - Test2 - elhamkhani - TriplyDB

The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

http://www.wikidata.org/entity/Q34992596

about

Rapid identification of antifungal compounds against Exserohilum rostratum using high throughput drug repurposing screens A safe lithium mimetic for bipolar disorder Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen Computational and Practical Aspects of Drug Repositioning The Tox21 robotic platform for the assessment of environmental chemicals--from vision to reality Drug repurposing and human parasitic protozoan diseases Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review Drug repositioning approaches for the discovery of new therapeutics for Alzheimer's disease Repositioning Clofazimine as a Macrophage-Targeting Photoacoustic Contrast Agent.Consistency of systematic chemical identifiers within and between small-molecule databases DrugCentral: online drug compendium Ambiguity of non-systematic chemical identifiers within and between small-molecule databases Many InChIs and quite some feat Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ Pharmacointeraction network models predict unknown drug-drug interactions Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway Identification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugs SWEETLEAD: an in silico database of approved drugs, regulated chemicals, and herbal isolates for computer-aided drug discovery A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseases Discovery of novel GPVI receptor antagonists by structure-based repurposing High-throughput screening for the identification of new therapeutic options for metastatic pheochromocytoma and paraganglioma In Silico Identification and In Vitro and In Vivo Validation of Anti-Psychotic Drug Fluspirilene as a Potential CDK2 Inhibitor and a Candidate Anti-Cancer Drug Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays Parallel worlds of public and commercial bioactive chemistry data PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers Chemical entity recognition in patents by combining dictionary-based and statistical approaches Current approaches for the discovery of drugs that deter substance and drug abuse.The Drug Repurposing Hub: a next-generation drug library and information resource Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS)Identification of repurposed small molecule drugs for chordoma therapy.Early repositioning through compound set enrichment analysis: a knowledge-recycling strategy.Computational drug repositioning: from data to therapeutics.Concordance and predictive value of two adverse drug event data sets.On InChI and evaluating the quality of cross-reference links Dealing with the Data Deluge: Handling the Multitude Of Chemical Biology Data Sources.An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software The successful treatment of hypercapnic respiratory failure with oral modafinil.

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P2860

The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

http://www.wikidata.org/entity/Q34992596

description

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011年の論文

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2011年論文

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2011年論文

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2011年论文

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Paul Shinn

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Ruili Huang

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Yuhong Wang

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P2860

Identification of a primary target of thalidomide teratogenicity

Predicting new molecular targets for known drugs

DrugBank: a knowledgebase for drugs, drug actions and drug targets

Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases

Neglected tropical diseases

Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action

Can the pharmaceutical industry reduce attrition rates?

Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome

A clinical drug library screen identifies astemizole as an antimalarial agent.

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

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Christopher P Austin

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