Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains

Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains

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http://www.wikidata.org/entity/Q35138471
The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expressionMechanisms and functions of Nrf2 signaling in Drosophila.Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy.The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expressionProteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).The Transcriptional Network Structure of a Myeloid Cell: A Computational Approach.Nach Is a Novel Subgroup at an Early Evolutionary Stage of the CNC-bZIP Subfamily Transcription Factors from the Marine Bacteria to HumansNrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues
P2860

Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains

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http://www.wikidata.org/entity/Q35138471
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Transcription factor Nrf1 is t ...... dic glucose-responsive domains
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Transcription factor Nrf1 is t ...... dic glucose-responsive domains
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Transcription factor Nrf1 is t ...... dic glucose-responsive domains
@ast
Transcription factor Nrf1 is t ...... dic glucose-responsive domains
@en
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Transcription factor Nrf1 is t ...... dic glucose-responsive domains
@ast
Transcription factor Nrf1 is t ...... dic glucose-responsive domains
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Transcription factor Nrf1 is t ...... dic glucose-responsive domains
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0093458
P407
P433
P478
P50
P577
P5875
P698
P932