Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity
about
The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathmTORC1 signaling activates NRF1 to increase cellular proteasome levelsGraded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome PathwayIntegration of the unfolded protein and oxidative stress responses through SKN-1/NrfSuppression of RNAi by dsRNA-degrading RNaseIII enzymes of viruses in animals and plantsThe conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegansUbiquitin-mediated response to microsporidia and virus infection in C. elegansInduction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathwaysThe C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expressionThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterTOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxORegulation of proteasome activity in health and diseaseA cytoprotective perspective on longevity regulationCe-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans.Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1.SKN-1/Nrf, a new unfolded protein response factor?20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegansTranscription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domainsDAF-16 target identification in C. elegans: past, present and future.Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegansGates, Channels, and Switches: Elements of the Proteasome MachineThe selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expressionLipid-mediated regulation of SKN-1/Nrf in response to germ cell absence.Wild worm embryogenesis harbors ubiquitous polygenic modifier variationInteractions between oxygen homeostasis, food availability, and hydrogen sulfide signaling.Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf.Isolation of a Hypomorphic skn-1 Allele That Does Not Require a Balancer for Maintenance.SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity.Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast.Mitochondrial SKN-1/Nrf mediates a conserved starvation response.18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures.The ubiquitin proteasome system in Caenorhabditis elegans and its regulation.The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases.Adaptive capacity to bacterial diet modulates aging in C. elegans.Host detection of pathogen-induced translational inhibition: a new pathogen-specific branch of the innate immune system?Tuning the proteasome to brighten the end of the journey.Co-translational mechanisms of quality control of newly synthesized polypeptides.Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity.Immunohistochemical analysis reveals variations in proteasome tissue expression in C. elegans
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P2860
Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@ast
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@en
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@nl
type
label
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@ast
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@en
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@nl
prefLabel
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@ast
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@en
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@nl
P2093
P2860
P3181
P1433
P1476
Specific SKN-1/Nrf stress resp ...... gation and proteasome activity
@en
P2093
Congyu Jin
Olli Matilainen
T Keith Blackwell
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1002119
P407
P577
2011-06-09T00:00:00Z