A central function for perlecan in skeletal muscle and cardiovascular development
about
Proteoglycan form and function: A comprehensive nomenclature of proteoglycansEndorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonismEndorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cellsPerlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis.The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagyDecoding the Matrix: Instructive Roles of Proteoglycan ReceptorsHanging on for the ride: adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and diseaseA current view of perlecan in physiology and pathology: A mosaic of functions.A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis.Mtmr8 is essential for vasculature development in zebrafish embryos.Embryonic mouse blood flow and oxygen correlate with early pancreatic differentiationThe Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development.Endorepellin evokes autophagy in endothelial cellsNGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathyPerlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition.Blood vessel repair and regeneration in the ischaemic heartDecorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.Collagen type IV and Perlecan exhibit dynamic localization in the Allantoic Core Domain, a putative stem cell niche in the murine allantoisPerlecan maintains microvessel integrity in vivo and modulates their formation in vitroThe proteoglycan Trol controls the architecture of the extracellular matrix and balances proliferation and differentiation of blood progenitors in the Drosophila lymph glandDecorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factLaminin-211 in skeletal muscle function.The role of extracellular matrix in vascular branching morphogenesisEndostatin and endorepellin: A common route of action for similar angiostatic cancer avengersProteoglycans in cancer biology, tumour microenvironment and angiogenesis.Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept.Diverse cell signaling events modulated by perlecan.In vitro and in vivo characterization of the anticancer activity of Thai stingless bee (Tetragonula laeviceps) cerumenThe role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.Force measurement during contraction to assess muscle function in zebrafish larvae.Soft texture of atlantic salmon fillets is associated with glycogen accumulation.EphA2 is a functional receptor for the growth factor progranulin.Basement membrane components are key players in specialized extracellular matrices.Urinary biomarkers of physical activity: candidates and clinical utility.The cardiovascular triad of dysfunctional angiogenesis.The nature and biology of basement membranes.Endorepellin-evoked Autophagy Contributes to Angiostasis.At the Start of the Sarcomere: A Previously Unrecognized Role for Myosin Chaperones and Associated Proteins during Early Myofibrillogenesis.
P2860
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P2860
A central function for perlecan in skeletal muscle and cardiovascular development
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A central function for perlecan in skeletal muscle and cardiovascular development
@ast
A central function for perlecan in skeletal muscle and cardiovascular development
@en
A central function for perlecan in skeletal muscle and cardiovascular development
@nl
type
label
A central function for perlecan in skeletal muscle and cardiovascular development
@ast
A central function for perlecan in skeletal muscle and cardiovascular development
@en
A central function for perlecan in skeletal muscle and cardiovascular development
@nl
prefLabel
A central function for perlecan in skeletal muscle and cardiovascular development
@ast
A central function for perlecan in skeletal muscle and cardiovascular development
@en
A central function for perlecan in skeletal muscle and cardiovascular development
@nl
P2093
P2860
P356
P1476
A central function for perlecan in skeletal muscle and cardiovascular development
@en
P2093
Angela McQuillan
Jason J Zoeller
Shiu-Ying Ho
P2860
P304
P356
10.1083/JCB.200708022
P407
P577
2008-04-01T00:00:00Z