Deoxyhypusine hydroxylase is a Fe(II)-dependent, HEAT-repeat enzyme. Identification of amino acid residues critical for Fe(II) binding and catalysis [corrected].
about
Specificity of the deoxyhypusine hydroxylase-eukaryotic translation initiation factor (eIF5A) interaction: identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5APosttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modificationA novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformationChemosensory regulation of a HEAT-repeat protein couples aggregation and sporulation in Myxococcus xanthusIron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase.Evidence for conformational changes in the yeast deoxyhypusine hydroxylase Lia1 upon iron displacement from its active site.Advances in iron chelation: an update.A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani.The hypusine-containing translation factor eIF5A.Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancerPhenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcriptionMolecular cloning and functional expression of bovine deoxyhypusine hydroxylase cDNA and homologsRole of cellular iron and oxygen in the regulation of HIV-1 infection.The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.Human deoxyhypusine hydroxylase, an enzyme involved in regulating cell growth, activates O2 with a nonheme diiron centerStall no more at polyproline stretches with the translation elongation factors EF-P and IF-5A.X-ray absorption spectroscopic characterization of the diferric-peroxo intermediate of human deoxyhypusine hydroxylase in the presence of its substrate eIF5aHydrogen-Atom Transfer Oxidation with H2O2 Catalyzed by [FeII(1,2-bis(2,2'-bipyridyl-6-yl)ethane(H2O)2]2+: Likely Involvement of a (μ-Hydroxo)(μ-1,2-peroxo)diiron(III) Intermediate.DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A
P2860
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P2860
Deoxyhypusine hydroxylase is a Fe(II)-dependent, HEAT-repeat enzyme. Identification of amino acid residues critical for Fe(II) binding and catalysis [corrected].
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@ast
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@en
type
label
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@ast
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@en
prefLabel
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@ast
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@en
P2093
P2860
P356
P1476
Deoxyhypusine hydroxylase is a ...... ing and catalysis [corrected].
@en
P2093
Edith C Wolff
Jessica K Bell
Kee Ryeon Kang
Myung Hee Park
Peter McPhie
Yeon Sook Kim
P2860
P304
13217-13225
P356
10.1074/JBC.M601081200
P407
P577
2006-03-13T00:00:00Z