SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
about
The NCI-60 Methylome and Its Integration into CellMiner.Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.Replication protein A and more: single-stranded DNA-binding proteins in eukaryotic cells.RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response.Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma.Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition.Unravelling the biology of SCLC: implications for therapy.Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.G9a coordinates with the RPA complex to promote DNA damage repair and cell survival.Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update.AUNIP/C1orf135 directs DNA double-strand breaks towards the homologous recombination repair pathway.Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine.Differential RPA-1 and RAD-51 recruitment in vivo throughout the C. elegans germline, as revealed by laser microirradiation.Overcoming resistance to DNA targeted agents by epigenetic activation of Schlafen 11 (SLFN11) expression with class I histone deacetylase inhibitors.SLFN11 Blocks Stressed Replication Forks Independently of ATR.Targeting DNA damage repair in small cell lung cancer and the biomarker landscape.Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.Transcriptional deregulation underlying the pathogenesis of small cell lung cancer.
P2860
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P2860
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@ast
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@en
type
label
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@ast
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@en
prefLabel
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@ast
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@en
P2093
P2860
P356
P1433
P1476
SLFN11 inhibits checkpoint maintenance and homologous recombination repair.
@en
P2093
Jiangman Lou
Junjie Chen
Mrinal Srivastava
Xin-hua Feng
P2860
P304
P356
10.15252/EMBR.201540964
P577
2015-12-09T00:00:00Z