about
Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesRadiosensitising effect of electrochemotherapy with bleomycin in LPB sarcoma cells and tumors in mice.Mechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates.Role of endoplasmic reticulum stress in drug-induced toxicityRole of redoximiRs in fibrogenesisDNA damage and repair in plants - from models to cropsSources of DNA double-strand breaks and models of recombinational DNA repairFlavoenzymes: versatile catalysts in biosynthetic pathwaysModulation of bleomycin-induced lung fibrosis by pegylated hyaluronidase and dopamine receptor antagonist in miceCrystal structure of DNA-bound Co(III){middle dot}bleomycin B2: Insights on intercalation and minor groove bindingStructure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+cofactorFunctional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.Adenovirus dodecahedron, as a drug delivery vectorHomeodomain interacting protein kinase 2 activation compromises endothelial cell response to laminar flow: protective role of p21(waf1,cip1,sdi1)Phf14, a novel regulator of mesenchyme growth via platelet-derived growth factor (PDGF) receptor-αInhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in miceMechanisms and Consequences of Double-Strand DNA Break Formation in ChromatinMechanisms of fibrosis: therapeutic translation for fibrotic diseaseThe disaccharide moiety of bleomycin facilitates uptake by cancer cellsMetabolomics investigation of recombinant mTNFα production in Streptomyces lividans.Critical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin Pathway.The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892.The human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.Molecular mechanisms of hypoxia in cancer.Suppression of cancer growth by nonviral gene therapy based on a novel reactive oxygen species-responsive promoter.A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.14-3-3ε boosts bleomycin-induced DNA damage response by inhibiting the drug-resistant activity of MVPBleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells.Bleomycin-induced flagellate erythema: A case report and review of the literature.Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway.Possible structural role of the disaccharide unit in Fe-bleomycin before and after oxygen activation.Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury.Solution structure of Fe(II)-azide-bleomycin derived from NMR data: transition from Fe(II)-bleomycin to Fe(II)-azide-bleomycin as derived from NMR data and structural calculations.A short DNA sequence confers strong bleomycin binding to hairpin DNAsInhibition of short patch and long patch base excision repair by an oxidized abasic site.DNA interstrand cross-link formation initiated by reaction between singlet oxygen and a modified nucleotideProtein modification by adenine propenalCrystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin.Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cells
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Bleomycins: towards better therapeutics.
@ast
Bleomycins: towards better therapeutics.
@en
type
label
Bleomycins: towards better therapeutics.
@ast
Bleomycins: towards better therapeutics.
@en
prefLabel
Bleomycins: towards better therapeutics.
@ast
Bleomycins: towards better therapeutics.
@en
P2860
P356
P1476
Bleomycins: towards better therapeutics.
@en
P2093
Jingyang Chen
JoAnne Stubbe
P2860
P2888
P304
P356
10.1038/NRC1547
P407
P577
2005-02-01T00:00:00Z