Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors. - Test2 - elhamkhani - TriplyDB

Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors.

Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors.

http://www.wikidata.org/entity/Q36109893

about

Quantification of frequent-hitter behavior based on historical high-throughput screening data.Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2.3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine.Structural Analysis of Chemokine Receptor-Ligand Interactions.Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily.Repositioning organohalogen drugs: a case study for identification of potent B-Raf V600E inhibitors via docking and bioassay A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.Detecting similar binding pockets to enable systems polypharmacology.A public-private partnership to unlock the untargeted kinome.3D-e-Chem: Structural Cheminformatics Workflows for Computer-Aided Drug Discovery.Challenges in the design of multitarget drugs against multifactorial pathologies: a new life for medicinal chemistry?Predicting Molecular Targets for Small-Molecule Drugs with a Ligand-Based Interaction Fingerprint Approach.On the origins of drug polypharmacology

P2860

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P2860

Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors.

http://www.wikidata.org/entity/Q36109893

description

2012 nî lūn-bûn

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2012年の論文

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Life beyond kinases: structure ...... antagonist of 5-HT receptors.

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Life beyond kinases: structure ...... antagonist of 5-HT receptors.

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Life beyond kinases: structure ...... antagonist of 5-HT receptors.

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Life beyond kinases: structure ...... antagonist of 5-HT receptors.

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Life beyond kinases: structure ...... antagonist of 5-HT receptors.

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Journal of Medicinal Chemistry

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Life beyond kinases: structure ...... antagonist of 5-HT receptors.

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Bryan L Roth

http://www.w3.org/2001/XMLSchema#string

Gang Chen

http://www.w3.org/2001/XMLSchema#string

Guoliang Zhang

http://www.w3.org/2001/XMLSchema#string

Niu Huang

http://www.w3.org/2001/XMLSchema#string

Ryan Whaley

http://www.w3.org/2001/XMLSchema#string

Shaohui Wang

http://www.w3.org/2001/XMLSchema#string

Shiming Peng

http://www.w3.org/2001/XMLSchema#string

Simon X Wang

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Xi-Ping Huang

http://www.w3.org/2001/XMLSchema#string

Xingyu Lin

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P2860

DrugBank: a comprehensive resource for in silico drug discovery and exploration

Serotonin promotes tumor growth in human hepatocellular cancer

Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation

Hierarchical docking of databases of multiple ligand conformations

Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation

CDD: a Conserved Domain Database for the functional annotation of proteins

The impact of GPCR structures on pharmacology and structure-based drug design

Predicting new molecular targets for known drugs

Flexible ligand docking using conformational ensembles

Crystal structure of rhodopsin: A G protein-coupled receptor

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5749-5759

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10.1021/JM300338M

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12

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2012-06-19T00:00:00Z

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22694093

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3402552

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