A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.
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International Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsGeneric GPCR residue numbers - aligning topology maps while minding the gapsFunction-specific virtual screening for GPCR ligands using a combined scoring method3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine.The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity.Histamine pharmacology: four years on.Polypharmacology: in silico methods of ligand design and development.Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands.Benchmarking of protein descriptor sets in proteochemometric modeling (part 2): modeling performance of 13 amino acid descriptor sets.The Target Residence Time of Antihistamines Determines Their Antagonism of the G Protein-Coupled Histamine H1 Receptor.Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants.A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?Identifying human diamine sensors for death related putrescine and cadaverine molecules.3D-e-Chem: Structural Cheminformatics Workflows for Computer-Aided Drug Discovery.Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology.Comparative molecular field analysis and molecular dynamics studies of the dopamine D2 receptor antagonists without a protonatable nitrogen atom.Halogen bonding enhances activity in a series of dual 5-HT6/D2 ligands designed in a hybrid bioisostere generation/virtual screening protocolStructure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor
P2860
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P2860
A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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name
A structural chemogenomics ana ...... tamine receptor ligand design.
@en
A structural chemogenomics ana ...... tamine receptor ligand design.
@nl
type
label
A structural chemogenomics ana ...... tamine receptor ligand design.
@en
A structural chemogenomics ana ...... tamine receptor ligand design.
@nl
prefLabel
A structural chemogenomics ana ...... tamine receptor ligand design.
@en
A structural chemogenomics ana ...... tamine receptor ligand design.
@nl
P2093
P2860
P356
P1476
A structural chemogenomics ana ...... tamine receptor ligand design.
@en
P2093
A J Kooistra
C de Graaf
I J P de Esch
P2860
P304
P356
10.1111/BPH.12248
P407
P577
2013-09-01T00:00:00Z