Discovery of histone deacetylase 8 selective inhibitors.
about
Role of histone deacetylases in pancreas: Implications for pathogenesis and therapySmall molecule inhibitors of zinc-dependent histone deacetylasesRadionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brainA novel HDAC inhibitor with a hydroxy-pyrimidine scaffoldCrebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Potential non-oncological applications of histone deacetylase inhibitors.Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction.Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.In-Bead Screening of Hydroxamic Acids for the Identification of HDAC Inhibitors.Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myelomaNatural chalcones as dual inhibitors of HDACs and NF-κB.Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agentsHistone deacetylases and their role in asthma.Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed.Potential of chromatin modifying compounds for the treatment of Alzheimer's disease.Targeting class I histone deacetylases in cancer therapy.Epigenetic regulation of inflammation: progressing from broad acting histone deacetylase (HDAC) inhibitors to targeting specific HDACs.Towards selective inhibition of histone deacetylase isoforms: what has been achieved, where we are and what will be next.Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors.An overview of investigational Histone deacetylase inhibitors (HDACis) for the treatment of non-Hodgkin's lymphoma.Targeting histone deacetylase 8 as a therapeutic approach to cancer and neurodegenerative diseases.Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylase 8-selective inhibitors.Selective histone deacetylase small molecule inhibitors: recent progress and perspectives.Synthesis and biological evaluation of ortho-aryl N-hydroxycinnamides as potent histone deacetylase (HDAC) 8 isoform-selective inhibitors.Development of a Potent and Selective HDAC8 Inhibitor.AB3-Loaded and Tumor-Targeted Unimolecular Micelles for Medullary Thyroid Cancer Treatment.Structure-activity relationships of hydroxamate-based histone deacetylase-8 inhibitors: reality behind anticancer drug discovery.Novel analogs targeting histone deacetylase suppress aggressive thyroid cancer cell growth and induce re-differentiation.Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue.Overview of the Classical Histone Deacetylase Enzymes and Histone Deacetylase Inhibitors
P2860
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P2860
Discovery of histone deacetylase 8 selective inhibitors.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Discovery of histone deacetylase 8 selective inhibitors.
@ast
Discovery of histone deacetylase 8 selective inhibitors.
@en
type
label
Discovery of histone deacetylase 8 selective inhibitors.
@ast
Discovery of histone deacetylase 8 selective inhibitors.
@en
prefLabel
Discovery of histone deacetylase 8 selective inhibitors.
@ast
Discovery of histone deacetylase 8 selective inhibitors.
@en
P2093
P2860
P1476
Discovery of histone deacetylase 8 selective inhibitors.
@en
P2093
Edward F Greenberg
James E Bradner
Stuart L Schreiber
Tuoping Luo
Weiping Tang
P2860
P304
P356
10.1016/J.BMCL.2011.01.134
P407
P577
2011-02-02T00:00:00Z