Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancer
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Histone lysine demethylases in Drosophila melanogasterPharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studiesAn high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitorsScreen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistanceHistone demethylase RBP2 is critical for breast cancer progression and metastasis.Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cellsPan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotypeIdentification of Jumonji AT-Rich Interactive Domain 1A Inhibitors and Their Effect on Cancer Cells.Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair.Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse CompoundsIntegrative genomic and transcriptomic analysis for pinpointing recurrent alterations of plant homeodomain genes and their clinical significance in breast cancer.Inhibitors of Protein Methyltransferases and Demethylases.The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.Connexin 26 is down-regulated by KDM5B in the progression of bladder cancer.PI3K/AKT Signaling Regulates H3K4 Methylation in Breast CancerJARID1 Histone Demethylases: Emerging Targets in Cancer.Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.Double duty: ZMYND8 in the DNA damage response and cancer.Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer.Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion.The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila.KDM5A Regulates a Translational Program that Controls p53 Protein ExpressionEpigenetic Targeting of GlioblastomaTumor evolution and chemoresistance in ovarian cancerKDM5 histone demethylases repress immune response via suppression of STING
P2860
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P2860
Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancer
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Genomic amplification and a ro ...... e demethylase in breast cancer
@ast
Genomic amplification and a ro ...... e demethylase in breast cancer
@en
type
label
Genomic amplification and a ro ...... e demethylase in breast cancer
@ast
Genomic amplification and a ro ...... e demethylase in breast cancer
@en
prefLabel
Genomic amplification and a ro ...... e demethylase in breast cancer
@ast
Genomic amplification and a ro ...... e demethylase in breast cancer
@en
P2093
P2860
P1476
Genomic amplification and a ro ...... e demethylase in breast cancer
@en
P2093
Alan Dombkowski
Andreana Holowatyj
Jinling Hou
Julie L Boerner
Kezhong Zhang
Zeng-Quan Yang
P2860
P304
P407
P577
2012-07-22T00:00:00Z