The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells
about
Molecular classification and prediction in gastric cancerHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionInhibition of 2-oxoglutarate dependent oxygenasesRBP2 induces epithelial-mesenchymal transition in non-small cell lung cancerAn high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitorsScreen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistancePotent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiationHistone demethylase RBP2 is critical for breast cancer progression and metastasis.H3K4 demethylase activities repress proliferative and postmitotic aging.The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer.Epigenetics: an emerging player in gastric cancerCritical role of histone demethylase RBP2 in human gastric cancer angiogenesis.Retinoblastoma binding protein 2 (RBP2) promotes HIF-1α-VEGF-induced angiogenesis of non-small cell lung cancer via the Akt pathway.Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells.Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes.Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.Histone demethylase retinoblastoma binding protein 2 is overexpressed in hepatocellular carcinoma and negatively regulated by hsa-miR-212.Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia.Identification of Jumonji AT-Rich Interactive Domain 1A Inhibitors and Their Effect on Cancer Cells.JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells.RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2.Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair.Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancerHistone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-β1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit.DNA and histone methylation in gastric carcinogenesisMiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network.Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype.Overexpression of JARID1B promotes differentiation via SHIP1/AKT signaling in human hypopharyngeal squamous cell carcinoma.Histone demethylase retinoblastoma binding protein 2 regulates the expression of α-smooth muscle actin and vimentin in cirrhotic livers.Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.The methylation landscape of tumour metastasis.Context-specific regulation of cancer epigenomes by histone and transcription factor methylation.Roles of histone methyl-modifying enzymes in development and progression of cancer.Chromatin dynamics: H3K4 methylation and H3 variant replacement during development and in cancer.Targeting Histone Demethylases: A New Avenue for the Fight against Cancer.Inhibitors of Protein Methyltransferases and Demethylases.MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.
P2860
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P2860
The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells
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2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@ast
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@en
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@nl
type
label
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@ast
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@en
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@nl
prefLabel
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@ast
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@en
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@nl
P2093
P3181
P1433
P1476
The histone demethylase RBP2 I ...... ers senescence of cancer cells
@en
P2093
Jiping Zeng
Lixiang Wang
Magnus Björkholm
P304
P3181
P356
10.1053/J.GASTRO.2009.10.004
P407
P577
2010-03-01T00:00:00Z