Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction
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Overexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated AutophagyDevelopment of kinomic analyses to identify dysregulated signaling pathways in cells expressing cytoplasmic PrP.Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments.Identification of novel putative-binding proteins for cellular prion protein and a specific interaction with the STIP1 homology and U-Box-containing protein 1.Overexpression of p62/SQSTM1 promotes the degradations of abnormally accumulated PrP mutants in cytoplasm and relieves the associated cytotoxicities via autophagy-lysosome-dependent way.
P2860
Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@ast
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@en
type
label
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@ast
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@en
prefLabel
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@ast
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@en
P2093
P2860
P356
P1433
P1476
Heat shock protein 70 selectiv ...... ty via a molecular interaction
@en
P2093
Bao-Yun Zhang
Xiao-Ping Dong
P2860
P356
10.1186/1743-422X-9-303
P577
2012-12-06T00:00:00Z