BAF complexes facilitate decatenation of DNA by topoisomerase IIα
about
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutationMammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsSister chromatid decatenation: bridging the gaps in our knowledgeATP-dependent chromatin remodeling complexes as novel targets for cancer therapyChromatin features and the epigenetic regulation of pluripotency states in ESCsGenetic alterations in hepatocellular carcinoma: An updateTopoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction.DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth.Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation.Looping back to leap forward: transcription enters a new eraEZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors.Clinicopathologic and prognostic relevance of ARID1A protein loss in colorectal cancerFunctional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers.SWI/SNF complexes are required for full activation of the DNA-damage response.TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.Unravelling the genomic targets of small molecules using high-throughput sequencing.Topoisomerase IIα in chromosome instability and personalized cancer therapy.ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP InhibitorsOpposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzymeThe REST remodeling complex protects genomic integrity during embryonic neurogenesis.ARID1A and TERT promoter mutations in dedifferentiated meningioma.A noncatalytic function of the topoisomerase II CTD in Aurora B recruitment to inner centromeres during mitosis.BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.7SK-BAF axis controls pervasive transcription at enhancers.Topoisomerase II regulates yeast genes with singular chromatin architectures.ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progressionChd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes.Nuclear phosphoinositides and their impact on nuclear functions.The SWI/SNF tumor suppressor complex: Regulation of promoter nucleosomes and beyond.The emerging roles of ARID1A in tumor suppression.A rationale to target the SWI/SNF complex for cancer therapy.Vulnerabilities of mutant SWI/SNF complexes in cancer.Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instabilityTopoisomerase-mediated chromosomal break repair: an emerging player in many games.Molecular pathogenesis of ovarian clear cell carcinoma.
P2860
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P2860
BAF complexes facilitate decatenation of DNA by topoisomerase IIα
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
BAF complexes facilitate decatenation of DNA by topoisomerase IIα
@en
type
label
BAF complexes facilitate decatenation of DNA by topoisomerase IIα
@en
prefLabel
BAF complexes facilitate decatenation of DNA by topoisomerase IIα
@en
P2093
P2860
P921
P356
P1433
P1476
BAF complexes facilitate decatenation of DNA by topoisomerase IIα
@en
P2093
Andrey Korshunov
Diana C Hargreaves
Erik L Miller
Gerald R Crabtree
Kairong Cui
Marcel Kool
Yoon-Jae Cho
P2860
P2888
P304
P356
10.1038/NATURE12146
P407
P577
2013-05-22T00:00:00Z
P5875
P6179
1047065106