Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
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Non-B DB: a database of predicted non-B DNA-forming motifs in mammalian genomes5'-UTR RNA G-quadruplexes: translation regulation and targetingMetastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expressionZika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae FamilyG-quadruplexes and their regulatory roles in biologyMolecular dynamics simulations of G-DNA and perspectives on the simulation of nucleic acid structuresStructure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad LayersSelf-association of short DNA loops through minor groove C:G:G:C tetradsA G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad DynamicsSolution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic SequenceSolution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoterStructure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junctionFluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNASolution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequenceStacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activityRecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5′ End-Stacked Dimeric Parallel G-QuadruplexesSolution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loopsG-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex foldStructure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversityMonomer-dimer equilibrium for the 5'-5' stacking of propeller-type parallel-stranded G-quadruplexes: NMR structural studyDuplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamerSolution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3)Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genomeMetal Cations in G-Quadruplex Folding and StabilityThe G4 genomeDisordering of human telomeric G-quadruplex with novel antiproliferative anthrathiophenedioneFinding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMRAn RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It RegulatesMoD-QM/MM Structural Refinement Method: Characterization of Hydrogen Bonding in the Oxytricha nova G-QuadruplexSingle-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicasesHuman DHX9 helicase unwinds triple-helical DNA structuresConserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of LentivirusesVisualization of long human telomere mimics by single-molecule fluorescence imagingTopology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD.G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule bindingSuppression of hPOT1 in diploid human cells results in an hTERT-dependent alteration of telomere length dynamics.Genome-wide analyses of recombination prone regions predict role of DNA structural motif in recombination.Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germlinePutative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes.Molecular models for intrastrand DNA G-quadruplexes.
P2860
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P2860
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Human telomere, oncogenic prom ...... rgets for cancer therapeutics.
@en
type
label
Human telomere, oncogenic prom ...... rgets for cancer therapeutics.
@en
prefLabel
Human telomere, oncogenic prom ...... rgets for cancer therapeutics.
@en
P2093
P2860
P356
P1476
Human telomere, oncogenic prom ...... rgets for cancer therapeutics.
@en
P2093
Anh Tuân Phan
Dinshaw J Patel
Vitaly Kuryavyi
P2860
P304
P356
10.1093/NAR/GKM711
P407
P5008
P577
2007-10-02T00:00:00Z