The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism.
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The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate ReceptorsPregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway.Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies.A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activationBrief report: an open-label study of the neurosteroid pregnenolone in adults with autism spectrum disorderPregnenolone sulfate: from steroid metabolite to TRP channel ligand.PKCε and allopregnanolone: functional cross-talk at the GABAA receptor levelPregnenolone sulfate as a modulator of synaptic plasticity.Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats.Calcium-engaged Mechanisms of Nongenomic Action of Neurosteroids.Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents.An interview with David H Farb, Section Editor for Basic Pharmacology.Neuroactive Steroids: Receptor Interactions and Responses.Neuroactive Steroids: Receptor Interactions and Responses.Adrenocorticotropin Acutely Regulates Pregnenolone Sulfate Production by the Human Adrenal In Vivo and In Vitro.Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia.
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P2860
The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@en
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@nl
type
label
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@en
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@nl
prefLabel
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@en
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@nl
P2093
P2860
P50
P356
P1476
The neuroactive steroid pregne ...... and Ca2+-dependent mechanism.
@en
P2093
Conor Smith
Emmanuel Kostakis
Kyle G Richards
Ming-Kuei Jang
Stella C Martin
P2860
P304
P356
10.1124/MOL.113.085696
P577
2013-05-28T00:00:00Z