Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function.
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Overexpression of s6 kinase 1 in brain tumours is associated with induction of hypoxia-responsive genes and predicts patients' survivalControl of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinaseThe TOR pathway comes of ageThe mTOR signalling pathway in human cancerTargeting the mTOR signaling network for cancer therapyCutting through the complexities of mTOR for the treatment of strokeShedding new light on neurodegenerative diseases through the mammalian target of rapamycinImpact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translationMechanisms limiting body growth in mammalsInvolvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells.Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic programRapamycin regulates stearoyl CoA desaturase 1 expression in breast cancerEstrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis.d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.Epigenetic engineering of ribosomal RNA genes enhances protein production.Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle.Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.Lymphangioleiomyomatosis and TSC2-/- cellsPrion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTORPRAS40 is an integral regulatory component of erythropoietin mTOR signaling and cytoprotectionCatalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors.Taking aim at Alzheimer's disease through the mammalian target of rapamycinResponse to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer.Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.Cellular effects of everolimus and sirolimus on podocytes.MiR-99a antitumor activity in human breast cancer cells through targeting of mTOR expression.Management options in triple-negative breast cancerFasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signalingGlycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferationLeucine Promotes Proliferation and Differentiation of Primary Preterm Rat Satellite Cells in Part through mTORC1 Signaling Pathway.Surviving hypoxia by modulation of mRNA translation rate.Mammalian target of rapamycin signaling in diabetic cardiovascular diseaseCircumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent mannerA Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascadeRestriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft modelNeuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease modelsRole of mTOR in anticancer drug resistance: perspectives for improved drug treatment.
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P2860
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Coordinate regulation of ribos ...... key mediator of mTOR function.
@en
Coordinate regulation of ribos ...... key mediator of mTOR function.
@nl
type
label
Coordinate regulation of ribos ...... key mediator of mTOR function.
@en
Coordinate regulation of ribos ...... key mediator of mTOR function.
@nl
prefLabel
Coordinate regulation of ribos ...... key mediator of mTOR function.
@en
Coordinate regulation of ribos ...... key mediator of mTOR function.
@nl
P2093
P1476
Coordinate regulation of ribos ...... key mediator of mTOR function
@en
P2093
Elissaveta B Tchoubrieva
Katarzyna Jastrzebski
Katherine M Hannan
Ross D Hannan
P304
P356
10.1080/08977190701779101
P50
P577
2007-08-01T00:00:00Z