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Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-AnalysisA metabolic perspective of Peto's paradox and cancerMetabolic control of cancer cell stemness: Lessons from iPS cellsSystematic review: Preventive and therapeutic applications of metformin in liver diseaseMetformin as a new anti-cancer drug in adrenocortical carcinomaMetformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cellsMetformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing ratsInhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).Do metformin a real anticarcinogen? A critical reappraisal of experimental data.Metformin alters DNA methylation genome-wide via the H19/SAHH axisMetformin pharmacogenomics: biomarkers to mechanisms.Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial.Prevention of tumor growth driven by PIK3CA and HPV oncogenes by targeting mTOR signaling with metformin in oral squamous carcinomas expressing OCT3.In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumorsAlternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformationMetformin inhibits growth of human glioblastoma cells and enhances therapeutic responsePhenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer CellsDisruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 statusMetformin induces ER stress-dependent apoptosis through miR-708-5p/NNAT pathway in prostate cancerMolecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase.Metformin for cancer and aging prevention: is it a time to make the long story short?The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to TumorigenesisHigh Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum.Repurposing old drugs to chemoprevention: the case of metformin.Metformin inhibits prostate cancer cell proliferation, migration, and tumor growth through upregulation of PEDF expressionTargeting cancer cell metabolism: The combination of metformin and 2-Deoxyglucose regulates apoptosis in ovarian cancer cells via p38 MAPK/JNK signaling pathway.Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.Metabostemness: a new cancer hallmark.The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases.The double-edged sword of AMPK signaling in cancer and its therapeutic implications.An updated review on cancer risk associated with incretin mimetics and enhancers.When fat becomes an ally of the enemy: adipose tissue as collaborator in human breast cancer.Metformin and prostate cancer stem cells: a novel therapeutic target.Metformin: risk-benefit profile with a focus on cancer.Targeting species-specific trace amine-associated receptor 1 ligands: to date perspective of the rational drug design process.Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma.lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1.Mitochondria and Cancer.Changes in [18F]Fluoro-2-deoxy-D-glucose incorporation induced by doxorubicin and anti-HER antibodies by breast cancer cells modulated by co-treatment with metformin and its effects on intracellular signalling.Differential effects of AMPK agonists on cell growth and metabolism
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Potential applications for biguanides in oncology
@en
Potential applications for biguanides in oncology.
@nl
type
label
Potential applications for biguanides in oncology
@en
Potential applications for biguanides in oncology.
@nl
prefLabel
Potential applications for biguanides in oncology
@en
Potential applications for biguanides in oncology.
@nl
P2860
P356
P1476
Potential applications for biguanides in oncology
@en
P2093
Michael Pollak
P2860
P304
P356
10.1172/JCI67232
P407
P577
2013-09-03T00:00:00Z