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The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 traffickingHuman CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complexSignal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1uExosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysisProtease signalling: the cutting edgeLysosomal membrane proteins and their central role in physiologyStructure of Rhomboid Protease in a Lipid EnvironmentActivity-based probes for rhomboid proteases discovered in a mass spectrometry-based assayA Novel Family of Soluble Minimal Scaffolds Provides Structural Insight into the Catalytic Domains of Integral Membrane MetallopeptidasesThe Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds CholesterolProteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate AffinityPresenilin promotes dietary copper uptakeThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency.Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins.Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substratesStructure of nicastrin unveils secrets of γ-secretaseA new class of rhomboid protease inhibitors discovered by activity-based fluorescence polarizationRoles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavageB cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.Features of Pro-σK important for cleavage by SpoIVFB, an intramembrane metalloprotease.Chemistry and biology of multicomponent reactions.Biochemical and structural insights into intramembrane metalloprotease mechanisms.Trafficking and proteolytic processing of RNF13, a model PA-TM-RING family endosomal membrane ubiquitin ligase.Rhomboid proteases in plants - still in square one?Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid ProteolysisWhy cells need intramembrane proteases - a mechanistic perspective.Intramembrane proteases as drug targets.A small-molecule FRET reporter for the real-time visualization of cell-surface proteolytic enzyme functions.An Inducible Reconstitution System for the Real-Time Kinetic Analysis of Protease Activity and Inhibition Inside the Membrane.Architectural and thermodynamic principles underlying intramembrane protease function.Protein-protected Au clusters as a new class of nanoscale biosensor for label-free fluorescence detection of proteasesThe intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain.Transmembrane Substrate Determinants for γ-Secretase Processing of APP CTFβ.Protein-directed synthesis of Mn-doped ZnS quantum dots: a dual-channel biosensor for two proteins.The fate of PrP GPI-anchor signal peptide is modulated by P238S pathogenic mutation.Structural biology: Membrane enzyme cuts a fine figure.Involvement of a conserved GFG motif region in substrate binding by RseP, an Escherichia coli S2P protease.Organocatalysis using aldehydes: the development and improvement of catalytic hydroaminations, hydrations and hydrolyses.Mechanisms of peptide hydrolysis by aspartyl and metalloproteases.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Intramembrane proteolysis
@en
Intramembrane proteolysis.
@nl
type
label
Intramembrane proteolysis
@en
Intramembrane proteolysis.
@nl
prefLabel
Intramembrane proteolysis
@en
Intramembrane proteolysis.
@nl
P2860
P356
P1433
P1476
Intramembrane proteolysis
@en
P2093
Michael S Wolfe
P2860
P304
P356
10.1021/CR8004197
P577
2009-04-01T00:00:00Z