Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry.
about
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancersInteractions of the human MCM-BP protein with MCM complex components and Dbf4How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage responseATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryoteImmortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state.Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.Cytometry of chromatin bound Mcm6 and PCNA identifies two states in G1 that are separated functionally by the G1 restriction point.Cell cycle arrest by transforming growth factor beta1 near G1/S is mediated by acute abrogation of prereplication complex activation involving an Rb-MCM interaction.Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomicsMinichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis.Reduced spermatogonial proliferation and decreased fertility in mice overexpressing cyclin E in spermatogoniaThe cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.The PS1 hairpin of Mcm3 is essential for viability and for DNA unwinding in vitro.Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle.Activation of postnatal neural stem cells requires nuclear receptor TLXThe presence of extra chromosomes leads to genomic instability.DNA replication licensing control and rereplication prevention.An integrated view of cyclin E function and regulationCell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness.Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis.Depletion of minichromosome maintenance protein 7 inhibits glioblastoma multiforme tumor growth in vivo.MYC Modulation around the CDK2/p27/SKP2 AxisMCM2 mediates progesterone-induced endometrial stromal cell proliferation and differentiation in mice.Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development.O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions
P2860
Q24294953-B7373E57-F8EF-4990-969C-3C8AF973953DQ24317620-CEA5510D-7404-4F64-88FE-A743E842FE7BQ24634200-F47346E0-1FCF-40AD-A2FA-844AE05C94B0Q28539430-334BE561-1BB0-4933-866D-940AED088923Q30523929-EB47BF8C-047B-4F5C-939B-91A10BE28F14Q30585968-8FB313C7-B372-4836-9FFC-01A097E09A08Q31122876-4EFB73AD-9370-4076-888F-F6303F324532Q33557789-29DCD5AE-3DF7-4637-B11D-A57FA4AFB073Q33614054-1ECFDF84-52BF-4D23-8065-73464CAB3802Q34297195-E733A612-F7C9-4E24-9837-6373EBFCE697Q34328693-26BE2B82-35ED-47E2-8FE8-F7A428604470Q34659934-B66B9C83-2650-4E72-9146-56F593F11F20Q35065983-909978B9-5E41-409D-BC89-FA8FE50FDAB0Q35070043-84C5D687-45AF-4295-9764-D141F5ABC3ADQ35090675-7017D6E2-64FF-4893-AF8A-B75AF6516DA3Q35334539-E4017894-149C-447E-99B7-D1ABA188F5DBQ36588666-6160F16E-657C-4F5D-8A62-9584CE60FB92Q37825828-0773CA64-C242-4350-BC5A-A8B4DAD1F804Q37970290-7DEB250F-2947-4F33-B110-D5F323BBF81EQ38728647-4D3B2F00-D98E-4FCD-B647-7DEF4FEE3528Q39063003-4EDE7263-D532-4B2B-A7C8-6049EB80B160Q39069322-CF22B41B-490E-4A92-871B-501FBB00207DQ39406924-D5DB9B42-34D0-4516-A915-5B4175EBECBBQ46590797-E8E96F75-2049-44D8-82B6-19CEFD5DCCA4Q47134358-CDB811B3-A8DA-4FFD-9532-4B8BC844AA9CQ57752771-7FDC5637-047F-4D0E-8AFA-D525A7844D64
P2860
Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@en
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@nl
type
label
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@en
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@nl
prefLabel
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@en
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@nl
P2093
P2860
P1433
P1476
Phosphorylation of Mcm2 by Cdc ...... ly during cell-cycle re-entry.
@en
P2093
James A Wohlschlegel
John R Yates
Juan Méndez
Leonardo K Teixeira
Li-Chiou Chuang
Martha Henze
Steven I Reed
P2860
P304
P356
10.1016/J.MOLCEL.2009.06.014
P577
2009-07-01T00:00:00Z