The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells
about
Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatinPrevention of DNA re-replication in eukaryotic cellsPreventing re-replication of chromosomal DNA.Functional domains of the Xenopus replication licensing factor Cdt1Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extractsSequential replication-coupled destruction at G1/S ensures genome stability.Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensingStructure and Mutagenesis Studies of the C-terminal Region of Licensing Factor Cdt1 Enable the Identification of Key Residues for Binding to Replicative Helicase Mcm ProteinsRegulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome StabilityHBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by GemininCell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteinsStructural basis for inhibition of the replication licensing factor Cdt1 by gemininRecruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachmentStress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factorChromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin.Origin licensing and p53 status regulate Cdk2 activity during G(1).Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Geminin inhibits a late step in the formation of human pre-replicative complexes.The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirusReplication licensing and the DNA damage checkpoint.Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis.Progesterone blocks estrogen-induced DNA synthesis through the inhibition of replication licensingA Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus.An inactive geminin mutant that binds cdt1Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damageThe involvement of acidic nucleoplasmic DNA-binding protein (And-1) in the regulation of prereplicative complex (pre-RC) assembly in human cells.Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1Molecular evolution of Drosophila Cdc6, an essential DNA replication-licensing gene, suggests an adaptive choice of replication origins.Classic "broken cell" techniques and newer live cell methods for cell cycle assessmentCdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.Activation of a human chromosomal replication origin by protein tethering.Analysis of re-replication from deregulated origin licensing by DNA fiber spreadingPhosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry.Understanding the limitations of radiation-induced cell cycle checkpoints.Relationship between DNA replication and the nuclear matrix.Flipping the switch from g1 to s phase with e3 ubiquitin ligasesCharacterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.FUCCI sensors: powerful new tools for analysis of cell proliferation.
P2860
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P2860
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The regulated association of C ...... ns and Cdc6 in mammalian cells
@ast
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en-gb
The regulated association of C ...... ns and Cdc6 in mammalian cells
@nl
type
label
The regulated association of C ...... ns and Cdc6 in mammalian cells
@ast
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en-gb
The regulated association of C ...... ns and Cdc6 in mammalian cells
@nl
prefLabel
The regulated association of C ...... ns and Cdc6 in mammalian cells
@ast
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en-gb
The regulated association of C ...... ns and Cdc6 in mammalian cells
@nl
P2093
P2860
P356
P1476
The regulated association of C ...... ns and Cdc6 in mammalian cells
@en
P2093
Dawn A D Chasse
Jeanette Gowen Cook
Joseph R Nevins
P2860
P304
P356
10.1074/JBC.M311933200
P407
P577
2004-03-05T00:00:00Z