An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface.
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Sequence and overexpression of GPP130/GIMPc: evidence for saturable pH-sensitive targeting of a type II early Golgi membrane proteinAP-3: an adaptor-like protein complex with ubiquitous expression.Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexesA large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complexThe highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter]Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteinsCytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathwayIdentification of lysosomal and Golgi localization signals in GAP and ARF domains of ARF domain protein 1Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated traffickingEndocytic clathrin-coated pit formation is independent of receptor internalization signal levelsDistinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartmentThe isoforms of proprotein convertase PC5 are sorted to different subcellular compartmentsThe neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway.Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins.Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p.'Shed' furin: mapping of the cleavage determinants and identification of its C-terminusThe AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosisThe ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.Human cytomegalovirus glycoprotein B contains autonomous determinants for vectorial targeting to apical membranes of polarized epithelial cells.An essential role for the proximal but not the distal cytoplasmic tail of glycoprotein M in murid herpesvirus 4 infection.Intracellular traffic of herpes simplex virus glycoprotein gE: characterization of the sorting signals required for its trans-Golgi network localization.Intracellular trafficking and localization of the pseudorabies virus Us9 type II envelope protein to host and viral membranes.Functional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels.Steady-state plasma membrane expression of human cytomegalovirus gB is determined by the phosphorylation state of Ser900The extracellular domain of herpes simplex virus gE is sufficient for accumulation at cell junctions but not for cell-to-cell spread.An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B is a signal for endocytosis from the plasma membraneIntracellular trafficking of the UL11 tegument protein of herpes simplex virus type 1.A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomesGolgi-to-late endosome trafficking of the yeast pheromone processing enzyme Ste13p is regulated by a phosphorylation site in its cytosolic domainBasolateral sorting of furin in MDCK cells requires a phenylalanine-isoleucine motif together with an acidic amino acid cluster.Adenovirus RIDbeta subunit contains a tyrosine residue that is critical for RID-mediated receptor internalization and inhibition of Fas- and TRAIL-induced apoptosisRole of cytoplasmic domain serines in intracellular trafficking of furin.Cargo recognition in clathrin-mediated endocytosisThe PC6B cytoplasmic domain contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments.Rab9-dependent retrograde transport and endosomal sorting of the endopeptidase furin.Endocytosed cation-independent mannose 6-phosphate receptor traffics via the endocytic recycling compartment en route to the trans-Golgi network and a subpopulation of late endosomes.GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomesTargeting of glycoprotein I (gE) of varicella-zoster virus to the trans-Golgi network by an AYRV sequence and an acidic amino acid-rich patch in the cytosolic domain of the molecule.Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms
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P2860
An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
An acidic sequence within the ...... ization from the cell surface.
@en
An acidic sequence within the ...... ization from the cell surface.
@nl
type
label
An acidic sequence within the ...... ization from the cell surface.
@en
An acidic sequence within the ...... ization from the cell surface.
@nl
prefLabel
An acidic sequence within the ...... ization from the cell surface.
@en
An acidic sequence within the ...... ization from the cell surface.
@nl
P2093
P2860
P1433
P1476
An acidic sequence within the ...... ization from the cell surface.
@en
P2093
Bonifacino JS
Humphrey J
Voorhees P
van Donselaar E
P2860
P304
P407
P577
1995-10-01T00:00:00Z