Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis. - Test2 - elhamkhani - TriplyDB

Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.

Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.

http://www.wikidata.org/entity/Q37679933

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Intracellular Calcium Dysregulation: Implications for Alzheimer's Disease Metals and Neuronal Metal Binding Proteins Implicated in Alzheimer's Disease There's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative Diseases MIRO GTPases in Mitochondrial Transport, Homeostasis and Pathology Tau-mediated synaptic damage in Alzheimer's disease Selective Transgenic Expression of Mutant Ubiquitin in Purkinje Cell Stripes in the Cerebellum.Selective filtering defect at the axon initial segment in Alzheimer's disease mouse models.Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation A γ-Secretase Independent Role for Presenilin in Calcium Homeostasis Impacts Mitochondrial Function and Morphology in Caenorhabditis elegans.A mutation in β-amyloid precursor protein renders SH‑SY5Y cells vulnerable to isoflurane toxicity: The role of inositol 1,4,5‑trisphosphate receptors.Losing sleep over mitochondria: a new player in the pathophysiology of fatal familial insomnia.Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases.Familial Alzheimer's Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants.CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline.Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons.AβPP/PS1 Transgenic Mice Show Sex Differences in the Cerebellum Associated with Aging.Wolfram syndrome: MAMs' connection?Mitofusin 2: from functions to disease.

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P2860

Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.

http://www.wikidata.org/entity/Q37679933

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 February 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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type

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Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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Journal of Clinical Investigation

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Familial Alzheimer's disease-a ...... ivity and calcium homeostasis.

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Andres Villegas

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Anne Korwitz

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Chris I De Zeeuw

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Christian Hagel

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Francisco Lopera

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Haibo Zhou

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Isidro Ferrer

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Kuikui Zhou

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Luis Velazquez-Perez

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Maria Fernanda Vinueza-Veloz

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P2860

Alzheimer's Disease

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons

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1552-1567

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scholarly article

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10.1172/JCI66407

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4

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124

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Diego Sepulveda-Falla

Chris I De Zeeuw

Alvaro A Barrera-Ocampo

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2014-02-24T00:00:00Z

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24569455

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Alzheimer's disease

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