Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
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Perspectives of differentiation therapies of acute myeloid leukemia: the search for the molecular basis of patients' variable responses to 1,25-dihydroxyvitamin d and vitamin d analogsRetinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cellsCistrome plasticity and mechanisms of cistrome reprogrammingGains of ubiquitylation sites in highly conserved proteins in the human lineage.ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias.Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia.The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.SIAH proteins: critical roles in leukemogenesis.All-trans retinoic acid in the treatment of pediatric acute promyelocytic leukemia.Origins of aberrant DNA methylation in acute myeloid leukemia.Synergistic targeted therapy for acute promyelocytic leukaemia: a model of translational research in human cancer.Chemosensitivity enhancement toward arsenic trioxide by inhibition of histone deacetylase in NB4 cell line.The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia.The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells.Redistribution of cell cycle by arsenic trioxide is associated with demethylation and expression changes of cell cycle related genes in acute promyelocytic leukemia cell line (NB4).Incident adverse events following therapy for acute promyelocytic leukemia.
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Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 January 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
@en
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia.
@nl
type
label
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
@en
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia.
@nl
prefLabel
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
@en
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia.
@nl
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P921
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P1476
Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
@en
P2093
H G Stunnenberg
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P2888
P304
P356
10.1038/SJ.BJC.6606095
P407
P577
2011-01-18T00:00:00Z