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Polyphenols as Modulator of Oxidative Stress in Cancer Disease: New Therapeutic StrategiesMacroautophagy and the oncogene-induced senescenceBiomarkers and molecular probes for cell death imaging and targeted therapeuticsTurning off AKT: PHLPP as a drug targetLong-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cellsDexamethasone reduces sensitivity to cisplatin by blunting p53-dependent cellular senescence in non-small cell lung cancerFailure of cell cleavage induces senescence in tetraploid primary cells.Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor.Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growthSilencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation.HiJAK'd Signaling; the STAT3 Paradox in Senescence and Cancer Progression.The role of senescent cells in ageing.Exploiting tumor cell senescence in anticancer therapySenescent cells and their secretory phenotype as targets for cancer therapy.Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia.p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis?Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamicsAntiprogestins in gynecological diseases.Senescence and apoptosis: dueling or complementary cell fates?Novel ferrocenyl derivatives exert anti-cancer effect in human lung cancer cells in vitro via inducing G1-phase arrest and senescence.Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.SIRT1 inactivation evokes antitumor activities in NSCLC through the tumor suppressor p27.Loss of JUNB/AP-1 promotes invasive prostate cancerNuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assayMetformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancerShp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.Metformin: multi-faceted protection against cancer.Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.TrkA is amplified in malignant melanoma patients and induces an anti-proliferative response in cell lines.AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine.Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation.Cellular senescence and cancer chemotherapy resistance.Regulation of senescence by microRNA biogenesis factors
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 June 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Pro-senescence therapy for cancer treatment.
@en
Pro-senescence therapy for cancer treatment.
@nl
type
label
Pro-senescence therapy for cancer treatment.
@en
Pro-senescence therapy for cancer treatment.
@nl
prefLabel
Pro-senescence therapy for cancer treatment.
@en
Pro-senescence therapy for cancer treatment.
@nl
P356
P1476
Pro-senescence therapy for cancer treatment.
@en
P2093
Andrea Alimonti
Caterina Nardella
P2888
P304
P356
10.1038/NRC3057
P407
P577
2011-06-24T00:00:00Z
P5875
P6179
1026980068