Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame? - Test2 - elhamkhani - TriplyDB

Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?

Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?

http://www.wikidata.org/entity/Q37954832

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Emerging gene therapies for retinal degenerations A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration Restoration of vision in the pde6β-deficient dog, a large animal model of rod-cone dystrophy Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation Sodium Iodate Produces a Strain-Dependent Retinal Oxidative Stress Response Measured In Vivo Using QUEST MRI.A high content screening approach to identify molecules neuroprotective for photoreceptor cells Prenatal hypoxia is associated with long-term retinal dysfunction in rats Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation.Endoplasmic Reticulum Stress and Unfolded Protein Response Pathways: Potential for Treating Age-related Retinal Degeneration Measuring In Vivo Free Radical Production by the Outer Retina.NGF eye-drops topical administration in patients with retinitis pigmentosa, a pilot study Insulin receptor signaling in cones.Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo Protein sorting, targeting and trafficking in photoreceptor cells Advances in Gene Therapy for Diseases of the Eye.Cytosolic reducing power preserves glutamate in retina.Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants Deficient glucose and glutamine metabolism in Aralar/AGC1/Slc25a12 knockout mice contributes to altered visual function Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice With the RPE65 Leu450Met Variant is Associated With Oxidative Stress and Apoptosis The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina.Gene therapy approaches for the treatment of retinal disorders AIPL1, A protein linked to blindness, is essential for the stability of enzymes mediating cGMP metabolism in cone photoreceptor cells.Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease.Protection against oxidative stress by vitamin D in cone cells.Quantifying the metabolic contribution to photoreceptor death in retinitis pigmentosa via a mathematical model.Pattern of retinal morphological and functional decay in a light-inducible, rhodopsin mutant mouse.Differential cytotoxic effects of 7-dehydrocholesterol-derived oxysterols on cultured retina-derived cells: Dependence on sterol structure, cell type, and density.Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa Reprogramming towards anabolism impedes degeneration in a preclinical model of retinitis pigmentosa.Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye.Retinal gene therapy coming of age mTORC1 sustains vision in retinitis pigmentosa.Loss of the cone-enriched caspase-7 does not affect secondary cone death in retinitis pigmentosa.Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration.Reprogramming the metabolome rescues retinal degeneration.Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia.

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Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?

http://www.wikidata.org/entity/Q37954832

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2011 nî lūn-bûn

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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name

Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Loss of daylight vision in ret ...... abolic dysregulation to blame?

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Claudio Punzo

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Constance L Cepko

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Wenjun Xiong

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Creative Commons Attribution-NonCommercial

P2860

Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration

A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo

HDAC4 regulates neuronal survival in normal and diseased retinas

mTOR: from growth signal integration to cancer, diabetes and ageing

Safety and efficacy of gene transfer for Leber's congenital amaurosis

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

Effect of gene therapy on visual function in Leber's congenital amaurosis

Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors

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vision disorder

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