Regulation of p53: a collaboration between Mdm2 and Mdmx.
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Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instabilityClinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancerCommunity structure detection for overlapping modules through mathematical programming in protein interaction networksThe Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung AdenocarcinomaProbing Difference in Binding Modes of Inhibitors to MDMX by Molecular Dynamics Simulations and Different Free Energy MethodsFunctional activation of mutant p53V172F by platinum analogs in cisplatin-resistant human tumor cells is dependent on serine-20 phosphorylationAberrant regulation of FBW7 in cancer.COP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.WIP1 phosphatase as pharmacological target in cancer therapy.Wiring miRNAs to pathways: a topological approach to integrate miRNA and mRNA expression profilesThe COP9 signalosome subunit 6 (CSN6): a potential oncogeneTargeting nucleocytoplasmic transport in cancer therapyThe MDM2 gene family.MDM4 overexpressed in acute myeloid leukemia patients with complex karyotype and wild-type TP53RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel.Targeted therapy in sarcomas other than GIST tumorsGenetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes.The alternative translated MDMX(p60) isoform regulates MDM2 activity.Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrumAnticancer potential of an ethanol extract of Asiasari radix against HCT-116 human colon cancer cells in vitro.On the interaction mechanisms of a p53 peptide and nutlin with the MDM2 and MDMX proteins: a Brownian dynamics study.Breaking down protein degradation mechanisms in cardiac muscle.DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destructionRap2b, a novel p53 target, regulates p53-mediated pro-survival functionTranscriptome profiling of granulosa cells from bovine ovarian follicles during atresia.Important molecular genetic markers of colorectal cancer.Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53.MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations.Variations within 3'-UTR of MDM4 gene contribute to clinical outcomes of advanced non-small cell lung cancer patients following platinum-based chemotherapy.Impact of EBV essential nuclear protein EBNA-3C on B-cell proliferation and apoptosis.Molecular diagnostics in soft tissue sarcomas and gastrointestinal stromal tumors.MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 statusAn EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation.Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients.Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction.Momordica charantia lectin exhibits antitumor activity towards hepatocellular carcinoma.Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability.p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3.
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Regulation of p53: a collaboration between Mdm2 and Mdmx.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Regulation of p53: a collaboration between Mdm2 and Mdmx.
@en
Regulation of p53: a collaboration between Mdm2 and Mdmx.
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type
label
Regulation of p53: a collaboration between Mdm2 and Mdmx.
@en
Regulation of p53: a collaboration between Mdm2 and Mdmx.
@nl
prefLabel
Regulation of p53: a collaboration between Mdm2 and Mdmx.
@en
Regulation of p53: a collaboration between Mdm2 and Mdmx.
@nl
P2093
P2860
P921
P356
P1433
P1476
Regulation of p53: a collaboration between Mdm2 and Mdmx.
@en
P2093
Dongsheng Pei
Junnian Zheng
Yanping Zhang
P2860
P304
P356
10.18632/ONCOTARGET.443
P407
P577
2012-03-01T00:00:00Z