Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.
about
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability DisordersHistone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferasesSirtuins in epigenetic regulationAdolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and BehaviorDysregulation of Acetylation Enzymes Inanimal Models of Psychostimulant use Disorders: Evolving StoriesDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseModulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseasesEpigenetic assays for chemical biology and drug discovery.Prefrontal consolidation supports the attainment of fear memory accuracyMolecular targets of chromatin repressive mark H3K9me3 in primate progenitor cells within adult neurogenic niches.Epigenetic memory: the Lamarckian brainHistone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson diseaseTranscription, epigenetics and ameliorative strategies in Huntington's Disease: a genome-wide perspectiveThe epigenetic landscape of alcoholism.Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model.Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer's Disease.Histone acetylation inhibitors promote axon growth in adult dorsal root ganglia neuronsp300 is not required for metabolic adaptation to endurance exercise training.Involvement of phosphorylated Apis mellifera CREB in gating a honeybee's behavioral response to an external stimulus.Acetyltransferases (HATs) as targets for neurological therapeuticsGenetic findings in obsessive-compulsive disorder connect to brain-derived neutrophic factor and mammalian target of rapamycin pathways: implications for drug development.Inhibition of different histone acetyltransferases (HATs) uncovers transcription-dependent and -independent acetylation-mediated mechanisms in memory formation.A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson's Disease.CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.Spatial genome organization and cognition.Integration of Bioorthogonal Probes and Q-FRET for the Detection of Histone Acetyltransferase Activity.Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation.Structure-Activity Relationships on Cinnamoyl Derivatives as Inhibitors of p300 Histone Acetyltransferase.Chemical probes and inhibitors of bromodomains outside the BET family.Epigenetic Etiology of Intellectual Disability.A role for histone acetylation mechanisms in adolescent alcohol exposure-induced deficits in hippocampal brain-derived neurotrophic factor expression and neurogenesis markers in adulthood.Insights into intermolecular interactions, electrostatic properties and the stability of C646 in the binding pocket of p300 histone acetyltransferase enzyme: a combined molecular dynamics and charge density study.Dissociable roles for histone acetyltransferases p300 and PCAF in hippocampus and perirhinal cortex-mediated object memory.Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases.[Epigenetic regulations and cerebral plasticity: towards new therapeutic options in neurodegenerative diseases?]Vitamin A deficiency impairs spatial learning and memory: the mechanism of abnormal CBP-dependent histone acetylation regulated by retinoic acid receptor alpha.Epigenetics, fragile X syndrome and transcriptional therapy.Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment.Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activatorUbiquitin Regulation: The Histone Modifying Enzyme's Story
P2860
Q26740071-09E71C41-834F-4247-B04E-A9FB84400B52Q27003952-F3B8F0FB-DE75-4728-9CB7-C7F6AABC6A5BQ27026861-B6D68FEB-DDF9-45AB-A16B-8261308C36AFQ28070096-1FDA4AB6-F588-42D7-8464-C2F59E5489C8Q28077090-34B45103-F5FB-4915-A461-41E8194A9275Q28088777-21BF3562-E437-484E-BB1C-76B1DE361849Q29247921-DF398565-3DE0-4A1C-B7E5-AE3CA6362FB8Q30358152-BC99540C-CA33-4CC3-A7D2-6CF408EEB7B8Q30405868-6AC79E78-A06F-4F21-BDB3-27DED3BEE7A5Q33972484-2A2567CC-2DED-4598-B063-5CDB646BF75BQ34323841-548CB5B2-847B-4BDE-B47B-CD67A9790BBEQ34683308-C4CC088D-781B-412B-9C74-1323A6C1DAA9Q35024695-61299EEB-8278-429A-AC2C-2C262DE110EEQ35111862-DECA420B-FCF9-491C-BF1F-3E110FA8F07AQ35112822-F6014E19-2C74-459F-B76B-338A1DC7CF8CQ35772931-80309AF3-7CBE-4268-923E-E6A20F4A841FQ35853603-8B21CE4E-7EFC-4BD8-ABEC-6EED28DD347CQ36705321-B614C49E-E0CA-40F4-86A9-B39A8CB03F23Q36812681-B7B78605-0A1E-469F-8C09-F67C229A300CQ37249167-BA6EC0A4-D1B8-4126-97A8-7BADBE972C4EQ38246625-0772803A-B34A-4BDC-95B1-BFDC8655227CQ38363468-5734B6E8-E7B0-42F3-97A8-CF8B1968ECEEQ38766912-63C73E49-4447-4935-B951-F6C1C8B1D922Q38815116-5C450DE2-EB34-4A5C-8081-F0BB4F0F7641Q38973220-07664F96-7C2B-4ABA-9E12-03FF83B69C57Q39376004-AD2FACA2-FABF-4F05-8261-6F5F8C5FAA1CQ39423291-4BB45D2E-C9AF-4515-B745-C1E58BC524D9Q40271872-C839CC4E-1535-43F0-B5FD-175E65D0A3D9Q47128083-0C7428B9-E6FA-4F56-BCC0-F4C693280F42Q47423681-E141267C-D90E-4211-8910-F9D7033B1E1BQ47575767-F4DECF73-CE47-4886-BAEB-5382CBD896F7Q47869988-A55E6919-3E66-4966-B29B-D8EBC74B5F35Q48701393-CECDDF04-8151-4813-A610-A8638CC860E2Q49949196-EEF7D03C-A869-492C-8424-AC9A927142E0Q50542122-1313AD78-6FF3-484F-B3B9-D89EC64B0FEDQ50660192-68801028-342F-479C-854F-F2A41AFE5313Q54765415-5077C784-44D3-4E9B-A34D-68CF55117982Q55248558-E55FE84E-F314-4C6B-A20C-0105619A65E4Q57054631-33BF4DB0-4E21-4371-84D7-37B075C0BDA7Q58700177-3B2CA4A7-0FE2-4138-BD20-6B93FDDC2046
P2860
Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Lysine acetyltransferases CBP ...... d neurodegenerative disorders.
@en
type
label
Lysine acetyltransferases CBP ...... d neurodegenerative disorders.
@en
prefLabel
Lysine acetyltransferases CBP ...... d neurodegenerative disorders.
@en
P2860
P50
P921
P1476
Lysine acetyltransferases CBP ...... nd neurodegenerative disorders
@en
P2093
Jose Viosca
P2860
P304
P356
10.2174/13816128113199990382
P5008
P577
2013-01-01T00:00:00Z