Phosphoinositide 3-kinases: a conserved family of signal transducers.
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Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytesHuman phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activityFyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinaseStructural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphatesClass II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptorsAkt phosphorylates and suppresses the transactivation of retinoic acid receptor alphaShould individual PI3 kinase isoforms be targeted in cancer?Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homologyConditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunitsDeficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C)Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alphaRole of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1The PI3K-PDK1 connection: more than just a road to PKBPhosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinaseIdentification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast.Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoPlatelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through AktThe N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrestIdentification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotesNegative regulation of PI 3-kinase by Ruk, a novel adaptor proteinA novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophyThe inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosolVav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activationPhosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinaseJACOP: a simple and robust method for the automated classification of protein sequences with modular architecture.Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.Endothelial nitric oxide synthase: a potential therapeutic target for cerebrovascular diseasesPharmacodynamic Biomarker Development for PI3K Pathway TherapeuticsFocus on PTEN RegulationPhosphatidylinositol 3-kinase and antiestrogen resistance in breast cancermTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsPhosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesisMolecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1).Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitorsGenetic evidence for a SPO1-dependent signaling pathway controlling meiotic progression in yeast.Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformationCarboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitroThe Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsOsteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cellsFoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
P2860
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P2860
Phosphoinositide 3-kinases: a conserved family of signal transducers.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Phosphoinositide 3-kinases: a conserved family of signal transducers.
@en
type
label
Phosphoinositide 3-kinases: a conserved family of signal transducers.
@en
prefLabel
Phosphoinositide 3-kinases: a conserved family of signal transducers.
@en
P2093
P921
P1476
Phosphoinositide 3-kinases: a conserved family of signal transducers.
@en
P2093
Leevers SJ
Panayotou G
Vanhaesebroeck B
Waterfield MD
P304
P356
10.1016/S0968-0004(97)01061-X
P577
1997-07-01T00:00:00Z