Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha
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Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblastsThe kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation siteEvidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivoKinetic mechanism of AKT/PKB enzyme familyInhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.The PI3K-PDK1 connection: more than just a road to PKBRegulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7IRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisSevere diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphataseActivation of protein kinase B by the A(1)-adenosine receptor in DDT(1)MF-2 cellsGlucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1)Akt-2 binds to Glut4-containing vesicles and phosphorylates their component proteins in response to insulinNeuregulin signaling on glucose transport in muscle cellsDomain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinaseIn Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of -Adrenergic Receptor SignalingIncreased Sensitivity to Noise-Induced Hearing Loss by Blockade of Endogenous PI3K/Akt Signaling.Akt isoforms differentially regulate neutrophil functionsRegulation of glycogen synthesis by amino acids in cultured human muscle cells.Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.Impaired PI 3-kinase activation in adipocytes from early growth-restricted male rats.Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B.The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction.Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblastsAkt regulates TPP1 homodimerization and telomere protection.Protein kinase C binding partners.The ontogeny of insulin signaling in the preterm baboon model.Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetesUp-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress.Molecular mechanism of insulin resistance in obesity and type 2 diabetes.Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain.A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes.Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation.Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling.An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo.Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cells
P2860
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P2860
Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Activation of protein kinase B ...... on with protein kinase B alpha
@ast
Activation of protein kinase B ...... on with protein kinase B alpha
@en
Activation of protein kinase B ...... on with protein kinase B alpha
@en-gb
Activation of protein kinase B ...... on with protein kinase B alpha
@nl
type
label
Activation of protein kinase B ...... on with protein kinase B alpha
@ast
Activation of protein kinase B ...... on with protein kinase B alpha
@en
Activation of protein kinase B ...... on with protein kinase B alpha
@en-gb
Activation of protein kinase B ...... on with protein kinase B alpha
@nl
prefLabel
Activation of protein kinase B ...... on with protein kinase B alpha
@ast
Activation of protein kinase B ...... on with protein kinase B alpha
@en
Activation of protein kinase B ...... on with protein kinase B alpha
@en-gb
Activation of protein kinase B ...... on with protein kinase B alpha
@nl
P2093
P2860
P3181
P356
P1433
P1476
Activation of protein kinase B ...... on with protein kinase B alpha
@en
P2093
P2860
P304
P3181
P356
10.1042/BJ3310299
P407
P478
331 ( Pt 1)
P577
1998-04-01T00:00:00Z