Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment
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Wnt/beta-catenin signaling and small molecule inhibitorsTankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt SignalingTankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin PunctaInteraction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cellsProteasome regulation by ADP-ribosylationFormation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.Wnt pathway activation by ADP-ribosylation.The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in DrosophilaThe Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2Structural Implications for Selective Targeting of PARPs.Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis.Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.Tankyrases as drug targets.Tankyrases: structure, function and therapeutic implications in cancer.Tankyrase Inhibitor Sensitizes Lung Cancer Cells to Endothelial Growth Factor Receptor (EGFR) Inhibition via Stabilizing Angiomotins and Inhibiting YAP Signaling.Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase--A Potential Strategy for Suppression of the Wnt Pathway.Molecular regulation and pharmacological targeting of the β-catenin destruction complex.Celebrating 30 years of Wnt signaling.Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.Structural insights into SAM domain-mediated tankyrase oligomerization.Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.Specificity of reversible ADP-ribosylation and regulation of cellular processes.Insights into the biogenesis, function, and regulation of ADP-ribosylation.Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.Identifying and Validating Tankyrase Binders and Substrates: A Candidate Approach.Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.
P2860
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P2860
Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@ast
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@en
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@nl
type
label
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@ast
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@en
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@nl
prefLabel
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@ast
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@en
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of a Tankyra ...... ankyrase substrate recruitment
@en
P2093
Seamus Morrone
Zhihong Cheng
P2860
P304
P3181
P356
10.1073/PNAS.1116618109
P407
P577
2012-01-31T00:00:00Z