Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
about
HIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchStructural and Computational Biology in the Design of Immunogenic Vaccine AntigensStructure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial VirusStructures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine designTrimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and GNatively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding siteImmunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing EpitopesThermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing AntibodiesHumanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope GlycoproteinHIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition.Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP TrimersStructure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity.Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41.Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response.Neutralizing Monoclonal Antibodies to Fight HIV-1: On the Threshold of Success.Rationally Targeted Mutations at the V1V2 Domain of the HIV-1 Envelope to Augment Virus Neutralization by Anti-V1V2 Monoclonal Antibodies.Evolution of coreceptor utilization to escape CCR5 antagonist therapy.Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein.Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer AntigensStructure of an HIV-2 gp120 in Complex with CD4.Roles of glycans in interactions between gp120 and HIV broadly neutralizing antibodiesIn silico Analysis of HIV-1 Env-gp120 Reveals Structural Bases for Viral Adaptation in Growth-Restrictive Cells.Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins.Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody.Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus.Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaquesHIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant.Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticlesUncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.Peptide triazole inactivators of HIV-1: how do they work and what is their potential?
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P2860
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
description
2015 nî lūn-bûn
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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2015 թվականի հուլիսին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@ast
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@en
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@nl
type
label
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@ast
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@en
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@nl
prefLabel
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@ast
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@en
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@nl
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P1476
Crystal structure, conformatio ...... f mature ligand-free HIV-1 Env
@en
P2093
Adam Harned
Adrian B McDermott
Aliaksandr Druz
Arne Schön
Baoshan Zhang
Bruce R Donald
Constance Williams
Daniel S Terry
Emma T Crooks
Ernesto Freire
P2860
P2888
P304
P3181
P356
10.1038/NSMB.3051
P50
P577
2015-07-01T00:00:00Z
P5875
P6179
1020579433