Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis
about
The microtubule-associated protein tumor overexpressed gene binds to the RNA trafficking protein heterogeneous nuclear ribonucleoprotein A2SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphaseCoordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle bindingThe KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAKContractile ring-independent localization of DdINCENP, a protein important for spindle stability and cytokinesis.CLIP-170 homologue and NUDE play overlapping roles in NUDF localization in Aspergillus nidulansMolecular requirements for kinetochore-associated microtubule formation in mammalian cells.MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics.KIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer.Mini spindles, the XMAP215 homologue, suppresses pausing of interphase microtubules in Drosophila.Control of MCAK degradation and removal from centromeresPLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activityThe transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival.LET-711, the Caenorhabditis elegans NOT1 ortholog, is required for spindle positioning and regulation of microtubule length in embryos.Interphase-specific phosphorylation-mediated regulation of tubulin dimer partitioning in human cells.Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.A +TIP for a smooth trip.Stu2p binds tubulin and undergoes an open-to-closed conformational change.Basic mechanism of eukaryotic chromosome segregation.B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins.Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancerMitotic centromere-associated kinesin is a novel marker for prognosis and lymph node metastasis in colorectal cancer.Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules.KIF-2C expression is correlated with poor prognosis of operable esophageal squamous cell carcinoma male patients.Pulling it together: The mitotic function of TACC3.Molecular insight into the regulation and function of MCAK.Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cellsA small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells.Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells.Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin.Symplekin specifies mitotic fidelity by supporting microtubule dynamics.Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1.Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity.Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis.Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase.CaMKIIgamma-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formationAneugenic activity of Op18/stathmin is potentiated by the somatic Q18-->e mutation in leukemic cells.Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel.A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly.Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.
P2860
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P2860
Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Differential functional interp ...... during interphase and mitosis
@en
Differential functional interp ...... during interphase and mitosis.
@nl
type
label
Differential functional interp ...... during interphase and mitosis
@en
Differential functional interp ...... during interphase and mitosis.
@nl
prefLabel
Differential functional interp ...... during interphase and mitosis
@en
Differential functional interp ...... during interphase and mitosis.
@nl
P2860
P356
P1433
P1476
Differential functional interp ...... during interphase and mitosis
@en
P2093
Per Holmfeldt
Sonja Stenmark
P2860
P304
P356
10.1038/SJ.EMBOJ.7600076
P407
P577
2004-01-29T00:00:00Z