Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
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To live or let die - complexity within the E2F1 pathwayObserved bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cellsAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerE2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B.Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome.Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance.Mechanism of the Neurospora circadian clock, a FREQUENCY-centric view.Fragment-based screening of the bromodomain of ATAD2.Lessons from yeast on emerging roles of the ATAD2 protein family in gene regulation and genome organization.Maintenance of nucleosomal balance in cis by conserved AAA-ATPase Yta7.ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, promotes esophageal squamous cell carcinomaDirect regulation of nucleosome density by the conserved AAA-ATPase Yta7ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma.Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.The Arabidopsis acetylated histone-binding protein BRAT1 forms a complex with BRP1 and prevents transcriptional silencing.The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection.CATP is a critical component of the Neurospora circadian clock by regulating the nucleosome occupancy rhythm at the frequency locusKDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and GlycolysisChemical synthesis of the ATAD2 bromodomain.Bromodomains as therapeutic targets.Progress in the discovery of small-molecule inhibitors of bromodomain--histone interactions.The bromodomain interaction module.Role of host cell factor-1 in cell cycle regulation.Bromodomains and their pharmacological inhibitors.The application of gold nanoparticles as a promising therapeutic approach in breast and ovarian cancer.Epigenomic regulation of oncogenesis by chromatin remodeling.Biological function and histone recognition of family IV bromodomain-containing proteins.Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancerDevelopmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex.Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop.ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication.Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome.ATAD2 Overexpression Identifies Colorectal Cancer Patients with Poor Prognosis and Drives Proliferation of Cancer Cells.Protein dynamics and structural waters in bromodomains.ATAD2 in cancer: a pharmacologically challenging but tractable target.The ATAD2 bromodomain binds different acetylation marks on the histone H4 in similar fuzzy complexes.Patent Highlights June-July 2017.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.
P2860
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P2860
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Chromatin loading of E2F-MLL c ...... eading a specific histone mark
@en
Chromatin loading of E2F-MLL c ...... ading a specific histone mark.
@nl
type
label
Chromatin loading of E2F-MLL c ...... eading a specific histone mark
@en
Chromatin loading of E2F-MLL c ...... ading a specific histone mark.
@nl
prefLabel
Chromatin loading of E2F-MLL c ...... eading a specific histone mark
@en
Chromatin loading of E2F-MLL c ...... ading a specific histone mark.
@nl
P2093
P2860
P356
P1476
Chromatin loading of E2F-MLL c ...... eading a specific histone mark
@en
P2093
Abigael T Gemo
Alexey S Revenko
Ekaterina V Kalashnikova
Hong-Wu Chen
June X Zou
P2860
P304
P356
10.1128/MCB.00484-10
P407
P577
2010-09-20T00:00:00Z